The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress
The inorganic polymer, polyphosphate (polyP), is present in all organisms examined to date with putative functions ranging from the maintenance of bioenergetics to stress resilience and protein homeostasis. Bioenergetics in the glacier-obligate, segmented worm, <i>Mesenchytraeus solifugus</...
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MDPI AG
2022-12-01
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| Series: | Biology |
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| Online Access: | https://www.mdpi.com/2079-7737/11/12/1771 |
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| author | Teresa Osorio Ernest R. Scoma Daniel H. Shain Diana S. Melissaratos Lindsey M. Riggs Vedangi Hambardikar Maria E. Solesio |
| author_facet | Teresa Osorio Ernest R. Scoma Daniel H. Shain Diana S. Melissaratos Lindsey M. Riggs Vedangi Hambardikar Maria E. Solesio |
| author_sort | Teresa Osorio |
| collection | DOAJ |
| description | The inorganic polymer, polyphosphate (polyP), is present in all organisms examined to date with putative functions ranging from the maintenance of bioenergetics to stress resilience and protein homeostasis. Bioenergetics in the glacier-obligate, segmented worm, <i>Mesenchytraeus solifugus</i>, is characterized by a paradoxical increase in intracellular ATP levels as temperatures decline. We show here that steady-state, mitochondrial polyP levels vary among species of Annelida, but were elevated only in <i>M. solifugus</i> in response to thermal stress. In contrast, polyP levels decreased with temperature in the mesophilic worm, <i>Enchytraeus crypticus</i>. These results identify fundamentally different bioenergetic strategies between closely related annelid worms, and suggest that I worm mitochondria maintain ATP and polyP in a dynamic equilibrium. |
| first_indexed | 2024-03-09T17:19:30Z |
| format | Article |
| id | doaj.art-c1d2ab1610ce42d8bfa7f8f9f26f74bb |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T17:19:30Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-c1d2ab1610ce42d8bfa7f8f9f26f74bb2023-11-24T13:23:12ZengMDPI AGBiology2079-77372022-12-011112177110.3390/biology11121771The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to StressTeresa Osorio0Ernest R. Scoma1Daniel H. Shain2Diana S. Melissaratos3Lindsey M. Riggs4Vedangi Hambardikar5Maria E. Solesio6Department of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USADepartment of Biology and CCIB, College of Arts and Sciences, Rutgers University, 201 Broadway, Camden, NJ 08103, USAThe inorganic polymer, polyphosphate (polyP), is present in all organisms examined to date with putative functions ranging from the maintenance of bioenergetics to stress resilience and protein homeostasis. Bioenergetics in the glacier-obligate, segmented worm, <i>Mesenchytraeus solifugus</i>, is characterized by a paradoxical increase in intracellular ATP levels as temperatures decline. We show here that steady-state, mitochondrial polyP levels vary among species of Annelida, but were elevated only in <i>M. solifugus</i> in response to thermal stress. In contrast, polyP levels decreased with temperature in the mesophilic worm, <i>Enchytraeus crypticus</i>. These results identify fundamentally different bioenergetic strategies between closely related annelid worms, and suggest that I worm mitochondria maintain ATP and polyP in a dynamic equilibrium.https://www.mdpi.com/2079-7737/11/12/1771inorganic polyphosphatepolyPATPannelidsstressice worms |
| spellingShingle | Teresa Osorio Ernest R. Scoma Daniel H. Shain Diana S. Melissaratos Lindsey M. Riggs Vedangi Hambardikar Maria E. Solesio The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress Biology inorganic polyphosphate polyP ATP annelids stress ice worms |
| title | The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress |
| title_full | The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress |
| title_fullStr | The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress |
| title_full_unstemmed | The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress |
| title_short | The Glacier Ice Worm, <i>Mesenchytraeus solifugus</i>, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress |
| title_sort | glacier ice worm i mesenchytraeus solifugus i elevates mitochondrial inorganic polyphosphate polyp levels in response to stress |
| topic | inorganic polyphosphate polyP ATP annelids stress ice worms |
| url | https://www.mdpi.com/2079-7737/11/12/1771 |
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