Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue.

Cell-autonomous and non-cell-autonomous roles for IRF6 during development of the tongue.

Interferon regulatory factor 6 (IRF6) encodes a highly conserved helix-turn-helix DNA binding protein and is a member of the interferon regulatory family of DNA transcription factors. Mutations in IRF6 lead to isolated and syndromic forms of cleft lip and palate, most notably Van der Woude syndrome...

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Bibliographic Details
Main Authors: Steven Goudy, Peggi Angel, Britni Jacobs, Cynthia Hill, Veronica Mainini, Arianna L Smith, Youssef A Kousa, Richard Caprioli, Lawrence S Prince, Scott Baldwin, Brian C Schutte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579850?pdf=render

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