Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2

Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2

Background/Aims: Recently, microRNAs (miRNAs) have been demonstrated to act as regulators of activation of hepatic stellate cells (HSCs). It is well known that the main profibrogenic inducer transforming growth factor-β1 (TGF-β1) contributes to HSC activation, which is a key event in liver fibrosis....

Full description

Bibliographic Details
Main Authors: Fujun Yu, BiCheng Chen, XuFei Fan, Guojun Li, Peihong Dong, Jianjian Zheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
MicroRNA-9-5p
DNA methylation
Hepatic stellate cell
TGFBR1
TGFBR2
Online Access:https://www.karger.com/Article/FullText/484303

Similar Items

Similar Items