FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development

FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development

Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant transformation, yet our knowledge of the underlying mechanisms controlling their development and functions remain incomplete. To reveal cell fate-determining pathways in NK cell progenitors (NKP), we uti...

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Bibliographic Details
Main Authors: Thuy T. Luu, Jonas Nørskov Søndergaard, Lucía Peña-Pérez, Shabnam Kharazi, Aleksandra Krstic, Stephan Meinke, Laurent Schmied, Nicolai Frengen, Yaser Heshmati, Marcin Kierczak, Thibault Bouderlique, Arnika Kathleen Wagner, Charlotte Gustafsson, Benedict J. Chambers, Adnane Achour, Claudia Kutter, Petter Höglund, Robert Månsson, Nadir Kadri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
innate lymphocyte cells (ILCs)
development
FOXO
natural killer cells
IL-15
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.854312/full

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