Histopathological Aspects of Gastritis in Children
Introduction Gastritis are particularly important in paediatric pathology in Romania, considering the large number of hospitalized cases in recent years and also the trend of increasing incidence of disease. Objectives The authors have proposed to investigate a homogeneous group of patients diagnose...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Romanian Society of Oral Rehabilitation
2012-10-01
|
| Series: | Romanian Journal of Oral Rehabilitation |
| Subjects: | |
| Online Access: | http://www.rjor.ro/histopathological-aspects-of-gastritis-in-children/?lang=ro |
| _version_ | 1818274146423930880 |
|---|---|
| author | Gabriela Păduraru Marin Burlea Doina Mihăilă Smaranda Diaconescu Claudia Olaru Ancuța Ignat Valeriu V. Lupu |
| author_facet | Gabriela Păduraru Marin Burlea Doina Mihăilă Smaranda Diaconescu Claudia Olaru Ancuța Ignat Valeriu V. Lupu |
| author_sort | Gabriela Păduraru |
| collection | DOAJ |
| description | Introduction Gastritis are particularly important in paediatric pathology in Romania, considering the large number of hospitalized cases in recent years and also the trend of increasing incidence of disease. Objectives The authors have proposed to investigate a homogeneous group of patients diagnosed with different types of gastritis, in order to identify those bacteriological, endoscopic and histopathological features that can change the vision about optimal therapeutic attitude, prognosis and disease progression. Methods We studied a group of 96 patients who were hospitalized in Vth Paediatrics Clinic, Children’s Emergency Hospital “Sf. Maria”, Iasi, between January 2008 and December 2010 who have been diagnosed with various forms of gastritis. The final diagnosis was confirmed endoscopically, bacteriologically and histopathologically. Results Histopathological examination revealed the presence of H. pylori and also microscopic lesions that were assessed according to Sydney System. The associated microscopic lesions were exclusively of chronic gastritis. Mild form of disease was much rarer for H. pylori infection (5.26%) compared with H. pylori negative group (54.34%).The presence of lymphoid follicles was more frequently objectified in H. pylori-positive group (28.94%) compared with H. pylori-negative group (8.69%). In the H. pylori-positive group, the moderately-active form prevailed (31.57%), followed by follicular active form (28.94%) and massive active form (13.15%), while in the H. pylori-negative group most frequently was mild chronic gastritis (54.34%). Conclusions Histopathological examination presents a high relevance in assessing microscopic gastric mucosal lesions and also their evolution after treatment. |
| first_indexed | 2024-12-12T22:09:13Z |
| format | Article |
| id | doaj.art-c1dcca07fa88425d92f05346cfa02832 |
| institution | Directory Open Access Journal |
| issn | 2066-7000 2601-4661 |
| language | English |
| last_indexed | 2024-12-12T22:09:13Z |
| publishDate | 2012-10-01 |
| publisher | Romanian Society of Oral Rehabilitation |
| record_format | Article |
| series | Romanian Journal of Oral Rehabilitation |
| spelling | doaj.art-c1dcca07fa88425d92f05346cfa028322022-12-22T00:10:18ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612012-10-01432328Histopathological Aspects of Gastritis in ChildrenGabriela Păduraru0Marin Burlea1Doina Mihăilă2Smaranda Diaconescu3Claudia Olaru4Ancuța Ignat5Valeriu V. Lupu6V th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaV th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaPathological anatomy laboratory, Children’s Emergency Hospital “Sf. Maria“, Iasi, RomaniaV th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaV th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaV th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaV th Paediatrics Clinic, Children’s Emergency Hospital "Sf. Maria", University of Medicine and Pharmacy "Grigore T. Popa" - Iasi, RomaniaIntroduction Gastritis are particularly important in paediatric pathology in Romania, considering the large number of hospitalized cases in recent years and also the trend of increasing incidence of disease. Objectives The authors have proposed to investigate a homogeneous group of patients diagnosed with different types of gastritis, in order to identify those bacteriological, endoscopic and histopathological features that can change the vision about optimal therapeutic attitude, prognosis and disease progression. Methods We studied a group of 96 patients who were hospitalized in Vth Paediatrics Clinic, Children’s Emergency Hospital “Sf. Maria”, Iasi, between January 2008 and December 2010 who have been diagnosed with various forms of gastritis. The final diagnosis was confirmed endoscopically, bacteriologically and histopathologically. Results Histopathological examination revealed the presence of H. pylori and also microscopic lesions that were assessed according to Sydney System. The associated microscopic lesions were exclusively of chronic gastritis. Mild form of disease was much rarer for H. pylori infection (5.26%) compared with H. pylori negative group (54.34%).The presence of lymphoid follicles was more frequently objectified in H. pylori-positive group (28.94%) compared with H. pylori-negative group (8.69%). In the H. pylori-positive group, the moderately-active form prevailed (31.57%), followed by follicular active form (28.94%) and massive active form (13.15%), while in the H. pylori-negative group most frequently was mild chronic gastritis (54.34%). Conclusions Histopathological examination presents a high relevance in assessing microscopic gastric mucosal lesions and also their evolution after treatment.http://www.rjor.ro/histopathological-aspects-of-gastritis-in-children/?lang=rogastritishelicobacter pylorihistopathology |
| spellingShingle | Gabriela Păduraru Marin Burlea Doina Mihăilă Smaranda Diaconescu Claudia Olaru Ancuța Ignat Valeriu V. Lupu Histopathological Aspects of Gastritis in Children Romanian Journal of Oral Rehabilitation gastritis helicobacter pylori histopathology |
| title | Histopathological Aspects of Gastritis in Children |
| title_full | Histopathological Aspects of Gastritis in Children |
| title_fullStr | Histopathological Aspects of Gastritis in Children |
| title_full_unstemmed | Histopathological Aspects of Gastritis in Children |
| title_short | Histopathological Aspects of Gastritis in Children |
| title_sort | histopathological aspects of gastritis in children |
| topic | gastritis helicobacter pylori histopathology |
| url | http://www.rjor.ro/histopathological-aspects-of-gastritis-in-children/?lang=ro |
| work_keys_str_mv | AT gabrielapaduraru histopathologicalaspectsofgastritisinchildren AT marinburlea histopathologicalaspectsofgastritisinchildren AT doinamihaila histopathologicalaspectsofgastritisinchildren AT smarandadiaconescu histopathologicalaspectsofgastritisinchildren AT claudiaolaru histopathologicalaspectsofgastritisinchildren AT ancutaignat histopathologicalaspectsofgastritisinchildren AT valeriuvlupu histopathologicalaspectsofgastritisinchildren |