Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) characterized by the coexistence of asthma, eosinophilia and characteristic histopathologic changes, is one of the primary systemic small vessel inflammation of unknown etiology. Cardiac involvement in the course of EGPA occur in 17–92% of patient...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2014-07-01
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| Series: | Rheumatology |
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| Online Access: | http://www.termedia.pl/Acute-heart-failure-with-left-ventricular-thrombus-in-the-course-of-eosinophilic-granulomatosis-with-polyangiitis,18,23175,1,1.html |
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| author | Anna Masiak Żaneta Smoleńska Zenobia Czuszyńska Zbigniew Zdrojewski |
| author_facet | Anna Masiak Żaneta Smoleńska Zenobia Czuszyńska Zbigniew Zdrojewski |
| author_sort | Anna Masiak |
| collection | DOAJ |
| description | Eosinophilic granulomatosis with polyangiitis (EGPA) characterized by the coexistence of asthma, eosinophilia and characteristic histopathologic changes, is one of the primary systemic small vessel inflammation of unknown etiology. Cardiac involvement in the course of EGPA occur in 17–92% of patients affecting poor prognosis and acting major cause of mortality in this group of patients. EGPA should always be considered in the differential diagnosis of acute heart failure, especially in young patients with no risk factors for coronary heart disease, and in patients with the presence of asthma, allergic rhinitis or nasal polyps. A rare complication of cardiac involvement is the thrombus formation in the left ventricular apex requiring anticoagulation. We report a case of 49 year old man with cardiac involvement that mimic acute coronary syndrome and led to the diagnosis of EGPA. |
| first_indexed | 2024-04-13T02:08:36Z |
| format | Article |
| id | doaj.art-c1e002401ed5411d83b744795956d2b9 |
| institution | Directory Open Access Journal |
| issn | 0034-6233 2084-9834 |
| language | English |
| last_indexed | 2024-04-13T02:08:36Z |
| publishDate | 2014-07-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Rheumatology |
| spelling | doaj.art-c1e002401ed5411d83b744795956d2b92022-12-22T03:07:23ZengTermedia Publishing HouseRheumatology0034-62332084-98342014-07-0152320721210.5114/reum.2014.4409223175Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitisAnna MasiakŻaneta SmoleńskaZenobia CzuszyńskaZbigniew ZdrojewskiEosinophilic granulomatosis with polyangiitis (EGPA) characterized by the coexistence of asthma, eosinophilia and characteristic histopathologic changes, is one of the primary systemic small vessel inflammation of unknown etiology. Cardiac involvement in the course of EGPA occur in 17–92% of patients affecting poor prognosis and acting major cause of mortality in this group of patients. EGPA should always be considered in the differential diagnosis of acute heart failure, especially in young patients with no risk factors for coronary heart disease, and in patients with the presence of asthma, allergic rhinitis or nasal polyps. A rare complication of cardiac involvement is the thrombus formation in the left ventricular apex requiring anticoagulation. We report a case of 49 year old man with cardiac involvement that mimic acute coronary syndrome and led to the diagnosis of EGPA.http://www.termedia.pl/Acute-heart-failure-with-left-ventricular-thrombus-in-the-course-of-eosinophilic-granulomatosis-with-polyangiitis,18,23175,1,1.htmleosinophilic granulomatosis with polyangiitis acute heart failure thrombosis |
| spellingShingle | Anna Masiak Żaneta Smoleńska Zenobia Czuszyńska Zbigniew Zdrojewski Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis Rheumatology eosinophilic granulomatosis with polyangiitis acute heart failure thrombosis |
| title | Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| title_full | Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| title_fullStr | Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| title_full_unstemmed | Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| title_short | Acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| title_sort | acute heart failure with left ventricular thrombus in the course of eosinophilic granulomatosis with polyangiitis |
| topic | eosinophilic granulomatosis with polyangiitis acute heart failure thrombosis |
| url | http://www.termedia.pl/Acute-heart-failure-with-left-ventricular-thrombus-in-the-course-of-eosinophilic-granulomatosis-with-polyangiitis,18,23175,1,1.html |
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