ALDHHIGH Population Is Regulated by the AKT/β-Catenin Pathway in a Cervical Cancer Model

ALDHHIGH Population Is Regulated by the AKT/β-Catenin Pathway in a Cervical Cancer Model

ALDH is an enzyme involved in different cellular processes, including cancer. It has been shown that a cellular subpopulation with high ALDH activity (ALDHHIGH) within a tumor is related to functional capabilities such as stemness, chemoresistance, and tumorigenicity. However, few studies have focus...

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Bibliographic Details
Main Authors: Miguel Ángel Sarabia-Sánchez, Eduardo Alvarado-Ortiz, Mariel Esperanza Toledo-Guzman, Alejandro García-Carrancá, Elizabeth Ortiz-Sánchez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
β-catenin
GSK3-β
ALDH
cervical cancer
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01039/full

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