Immunoreactivity parameters in cardiosurgery patients

In 51 patients, immune status was assessed before and after coronary aortic bypass graft (CABG) surgery. All participants were divided into two groups: Group I - without any post-surgery complications (n=23; 45,5%); Group II - with post-surgery infectious and inflammatory pathology (n=28, 54,5%). Ca...

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Main Authors: A. A. Silaev, E. P. Turmova, V. V. Volkov, E. V. Markelova, D. B. Andreev
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2005-10-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2362
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author A. A. Silaev
E. P. Turmova
V. V. Volkov
E. V. Markelova
D. B. Andreev
author_facet A. A. Silaev
E. P. Turmova
V. V. Volkov
E. V. Markelova
D. B. Andreev
author_sort A. A. Silaev
collection DOAJ
description In 51 patients, immune status was assessed before and after coronary aortic bypass graft (CABG) surgery. All participants were divided into two groups: Group I - without any post-surgery complications (n=23; 45,5%); Group II - with post-surgery infectious and inflammatory pathology (n=28, 54,5%). Cardiosurgery patients had immunocompetent cell distribution pathology, which reflected immunity status abnormalities. Functional cell activity was decreased, humoral immunity was disturbed. In patients with septic complications, these disturbances were observed before CABG, and after the intervention they were even more severe. Immune disturbances in cardiosurgery patients play an important part in post-operative complications' pathogenesis, and ask for active risk factor screening, as well as for preventive immunotropic therapy.
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spelling doaj.art-c1e2cb9c4aef493a924b8c612f7d67432023-03-29T21:23:12Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202005-10-010550542108Immunoreactivity parameters in cardiosurgery patientsA. A. Silaev0E. P. Turmova1V. V. Volkov2E. V. Markelova3D. B. Andreev4филиал НИИ кардиологии Томского научного центра СО РАМНФилиал НИИ кардиологии Дальневосточного научного центра СО РАМНфилиал НИИ кардиологии Томского научного центра СО РАМНВладивостокский государственный медицинский университетфилиал НИИ кардиологии Томского научного центра СО РАМНIn 51 patients, immune status was assessed before and after coronary aortic bypass graft (CABG) surgery. All participants were divided into two groups: Group I - without any post-surgery complications (n=23; 45,5%); Group II - with post-surgery infectious and inflammatory pathology (n=28, 54,5%). Cardiosurgery patients had immunocompetent cell distribution pathology, which reflected immunity status abnormalities. Functional cell activity was decreased, humoral immunity was disturbed. In patients with septic complications, these disturbances were observed before CABG, and after the intervention they were even more severe. Immune disturbances in cardiosurgery patients play an important part in post-operative complications' pathogenesis, and ask for active risk factor screening, as well as for preventive immunotropic therapy.https://russjcardiol.elpub.ru/jour/article/view/2362coronary aortic bypass graft surgeryseptic complicationsimmune statushumoral immunityabnormald ities
spellingShingle A. A. Silaev
E. P. Turmova
V. V. Volkov
E. V. Markelova
D. B. Andreev
Immunoreactivity parameters in cardiosurgery patients
Российский кардиологический журнал
coronary aortic bypass graft surgery
septic complications
immune status
humoral immunity
abnormald ities
title Immunoreactivity parameters in cardiosurgery patients
title_full Immunoreactivity parameters in cardiosurgery patients
title_fullStr Immunoreactivity parameters in cardiosurgery patients
title_full_unstemmed Immunoreactivity parameters in cardiosurgery patients
title_short Immunoreactivity parameters in cardiosurgery patients
title_sort immunoreactivity parameters in cardiosurgery patients
topic coronary aortic bypass graft surgery
septic complications
immune status
humoral immunity
abnormald ities
url https://russjcardiol.elpub.ru/jour/article/view/2362
work_keys_str_mv AT aasilaev immunoreactivityparametersincardiosurgerypatients
AT epturmova immunoreactivityparametersincardiosurgerypatients
AT vvvolkov immunoreactivityparametersincardiosurgerypatients
AT evmarkelova immunoreactivityparametersincardiosurgerypatients
AT dbandreev immunoreactivityparametersincardiosurgerypatients