Novel Chemically Modified Curcumin (CMC) Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis in B16F10 Mouse Melanoma Cells

Novel Chemically Modified Curcumin (CMC) Derivatives Inhibit Tyrosinase Activity and Melanin Synthesis in B16F10 Mouse Melanoma Cells

Skin hyperpigmentation disorders arise due to excessive production of the macromolecular pigment melanin catalyzed by the enzyme tyrosinase. Recently, the therapeutic use of curcumin for inhibiting tyrosinase activity and production of melanin have been recognized, but poor stability and solubility...

Full description

Bibliographic Details
Main Authors: Shilpi Goenka, Francis Johnson, Sanford R. Simon
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
curcumin
chemically modified curcumin
tyrosinase
enzyme kinetics
melanogenesis
α-glucosidase
Online Access:https://www.mdpi.com/2218-273X/11/5/674

Similar Items

Similar Items