Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint Inhibitor Therapy
Serum autoantibody markers have the advantages of easy specimen acquisition, simple detection technology and dynamic real-time monitoring. With the wide application of immune checkpoint inhibitors in the treatment of malignant tumors, autoantibody markers in predicting tumor immune checkpoint inhibi...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2022-07-01
|
| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2022.101.28 |
| _version_ | 1818041385757966336 |
|---|---|
| author | Liyuan DAI Xiaohong HAN |
| author_facet | Liyuan DAI Xiaohong HAN |
| author_sort | Liyuan DAI |
| collection | DOAJ |
| description | Serum autoantibody markers have the advantages of easy specimen acquisition, simple detection technology and dynamic real-time monitoring. With the wide application of immune checkpoint inhibitors in the treatment of malignant tumors, autoantibody markers in predicting tumor immune checkpoint inhibitors efficacy and forecasting irAEs (immune related adverse events) show good prediction of potential. This review mainly focused on the progress of autoantibody markers in the prediction of therapeutic effect and the monitoring of irAE in tumor immunotherapy. |
| first_indexed | 2024-12-10T08:29:35Z |
| format | Article |
| id | doaj.art-c1f90ff4c68747b8bc17639926ee2d24 |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-12-10T08:29:35Z |
| publishDate | 2022-07-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-c1f90ff4c68747b8bc17639926ee2d242022-12-22T01:56:09ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872022-07-0125753454010.3779/j.issn.1009-3419.2022.101.28Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor TherapyLiyuan DAI0Xiaohong HAN1Department of Clinical Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,
Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, ChinaClinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaSerum autoantibody markers have the advantages of easy specimen acquisition, simple detection technology and dynamic real-time monitoring. With the wide application of immune checkpoint inhibitors in the treatment of malignant tumors, autoantibody markers in predicting tumor immune checkpoint inhibitors efficacy and forecasting irAEs (immune related adverse events) show good prediction of potential. This review mainly focused on the progress of autoantibody markers in the prediction of therapeutic effect and the monitoring of irAE in tumor immunotherapy.http://dx.doi.org/10.3779/j.issn.1009-3419.2022.101.28immune checkpoint therapyiraeautoantibodyprognostic marker |
| spellingShingle | Liyuan DAI Xiaohong HAN Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint Inhibitor Therapy Chinese Journal of Lung Cancer immune checkpoint therapy irae autoantibody prognostic marker |
| title | Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor Therapy |
| title_full | Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor Therapy |
| title_fullStr | Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor Therapy |
| title_full_unstemmed | Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor Therapy |
| title_short | Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint
Inhibitor Therapy |
| title_sort | clinical value of autoantibody prognostic markers in tumor immune checkpoint
inhibitor therapy |
| topic | immune checkpoint therapy irae autoantibody prognostic marker |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2022.101.28 |
| work_keys_str_mv | AT liyuandai clinicalvalueofautoantibodyprognosticmarkersintumorimmunecheckpointinhibitortherapy AT xiaohonghan clinicalvalueofautoantibodyprognosticmarkersintumorimmunecheckpointinhibitortherapy |