Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum
Based on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than t...
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MDPI AG
2015-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/9/17483 |
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| author | Yang Ge Pingping Liu Rui Yang Liu Zhang Hongxing Chen Ibrahima Camara Yiqing Liu Wangpeng Shi |
| author_facet | Yang Ge Pingping Liu Rui Yang Liu Zhang Hongxing Chen Ibrahima Camara Yiqing Liu Wangpeng Shi |
| author_sort | Yang Ge |
| collection | DOAJ |
| description | Based on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than total alkaloids. The contact toxicity from these alkaloids against the aphid Lipaphis erysimi was significant, as the 24 h-LC50 values of alkaloids I, II, III and total alkaloids were 292.48, 367.21, 487.791 and 163.52 mg/L, respectively. The development disruption of S. litura larvae was tested, the pupation and emergence rates of S. litura decreased and the acute mortality of S. litura increased significantly by day 3 after being injected in their body cavity with 10–40 mg/L of total alkaloid. The ecdysone titer of treated S. litura larvae and prepupae declined with increasing alkaloid concentration. The alkaloids of Cynanchum mongolicum are potential insect growth inhibitors. |
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| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-11T05:39:58Z |
| publishDate | 2015-09-01 |
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| spelling | doaj.art-c1f9cf3c57184b6ea64de1d8ab28ef102022-12-22T01:19:09ZengMDPI AGMolecules1420-30492015-09-01209174831749210.3390/molecules200917483molecules200917483Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicumYang Ge0Pingping Liu1Rui Yang2Liu Zhang3Hongxing Chen4Ibrahima Camara5Yiqing Liu6Wangpeng Shi7College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaCollaborative Innovation Center of Special Plant Industry, Chongqing University of Arts and Sciences, Chongqing 402160, ChinaCollege of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, ChinaBased on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than total alkaloids. The contact toxicity from these alkaloids against the aphid Lipaphis erysimi was significant, as the 24 h-LC50 values of alkaloids I, II, III and total alkaloids were 292.48, 367.21, 487.791 and 163.52 mg/L, respectively. The development disruption of S. litura larvae was tested, the pupation and emergence rates of S. litura decreased and the acute mortality of S. litura increased significantly by day 3 after being injected in their body cavity with 10–40 mg/L of total alkaloid. The ecdysone titer of treated S. litura larvae and prepupae declined with increasing alkaloid concentration. The alkaloids of Cynanchum mongolicum are potential insect growth inhibitors.http://www.mdpi.com/1420-3049/20/9/17483Cynanchum mongolicumalkaloidsinsecticidal constituentsinsecticidal activitySpodoptera lituraLipaphis erysimi |
| spellingShingle | Yang Ge Pingping Liu Rui Yang Liu Zhang Hongxing Chen Ibrahima Camara Yiqing Liu Wangpeng Shi Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum Molecules Cynanchum mongolicum alkaloids insecticidal constituents insecticidal activity Spodoptera litura Lipaphis erysimi |
| title | Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum |
| title_full | Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum |
| title_fullStr | Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum |
| title_full_unstemmed | Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum |
| title_short | Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum |
| title_sort | insecticidal constituents and activity of alkaloids from cynanchum mongolicum |
| topic | Cynanchum mongolicum alkaloids insecticidal constituents insecticidal activity Spodoptera litura Lipaphis erysimi |
| url | http://www.mdpi.com/1420-3049/20/9/17483 |
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