Second-Generation Enamine-Type Schiff Bases as 2-Amino Acid-Derived Antifungals against <i>Fusarium oxysporum</i>: Microwave-Assisted Synthesis, In Vitro Activity, 3D-QSAR, and In Vivo Effect

Second-Generation Enamine-Type Schiff Bases as 2-Amino Acid-Derived Antifungals against <i>Fusarium oxysporum</i>: Microwave-Assisted Synthesis, In Vitro Activity, 3D-QSAR, and In Vivo Effect

In this manuscript, the synthesis of enamine-type Schiff bases <b>1–48</b> derived from the amino acids <i>L</i>-Ala, <i>L</i>-Tyr, and <i>L</i>-Phe was carried out. Their in vitro activity and in vivo protective effect against <i>Fusarium oxyspo...

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Bibliographic Details
Main Authors: Paola Borrego-Muñoz, Diego Cardenas, Felipe Ospina, Ericsson Coy-Barrera, Diego Quiroga
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Journal of Fungi
Subjects:
Schiff base
enamine
2-amino acids
antifungal activity
<i>Fusarium oxysporum</i>
QSAR-3D
Online Access:https://www.mdpi.com/2309-608X/9/1/113

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https://www.mdpi.com/2309-608X/9/1/113

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