Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE)
Background: Scant research has focused on posttraumatic stress disorder (PTSD) in the SCI population, despite high prevalence estimates. Fortunately, prolonged exposure therapy (PE) is a well-researched and highly effective treatment for PTSD. Our recent clinical trial showed that standard 12-sessio...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
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| Series: | Contemporary Clinical Trials Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451865422001478 |
| _version_ | 1811177472083886080 |
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| author | Mark B. Powers Megan E. Douglas Simon Driver Seema Sikka Rita Hamilton Chad Swank Librada Callender Christa Ochoa Monica Bennett Neil Stewart Gregory V. Chauvin Barbara O. Rothbaum Ann Marie Warren |
| author_facet | Mark B. Powers Megan E. Douglas Simon Driver Seema Sikka Rita Hamilton Chad Swank Librada Callender Christa Ochoa Monica Bennett Neil Stewart Gregory V. Chauvin Barbara O. Rothbaum Ann Marie Warren |
| author_sort | Mark B. Powers |
| collection | DOAJ |
| description | Background: Scant research has focused on posttraumatic stress disorder (PTSD) in the SCI population, despite high prevalence estimates. Fortunately, prolonged exposure therapy (PE) is a well-researched and highly effective treatment for PTSD. Our recent clinical trial showed that standard 12-session PE was effective for PTSD treatment among inpatients with SCI. Early intervention with brief PE (3-sessions) delivered in the emergency department has also been effective for PTSD prevention, but has not been tested among people post-SCI. Thus, we aim to conduct the first test of the Brief PE intervention to prevent PTSD among patients with SCI. Methods: Adults who have experienced a SCI (N = 200) will be randomly assigned during inpatient rehabilitation to either: (a) 3 60-min sessions of Brief PE (intervention group) or (b) treatment as usual (control group). Results: The primary outcome measure (PTSD symptoms measured by the PSSI-5) and secondary outcome measures (depression, anxiety, pain, quality of life, sleep disturbance, and resilience) will be assessed at baseline, 1-month, 3-months, and 6-months. Hierarchical linear modeling (HLM) will be used to evaluate the effectiveness of the PE intervention on PTSD and secondary outcomes. Descriptive statistics will examine feasibility and will include the number of participants enrolled, the number of sessions completed, fidelity of Brief PE delivery, and average scores for difficulty and helpfulness of the intervention scales for those randomized to intervention. Conclusions: Successful completion of this study will provide an evidence-based program to alleviate posttraumatic distress post spinal cord injury and prevent long-term development of PTSD. |
| first_indexed | 2024-04-11T06:02:25Z |
| format | Article |
| id | doaj.art-c1fd2679fe324ffdb4ed0b78a509341e |
| institution | Directory Open Access Journal |
| issn | 2451-8654 |
| language | English |
| last_indexed | 2024-04-11T06:02:25Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Contemporary Clinical Trials Communications |
| spelling | doaj.art-c1fd2679fe324ffdb4ed0b78a509341e2022-12-22T04:41:38ZengElsevierContemporary Clinical Trials Communications2451-86542022-12-0130101030Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE)Mark B. Powers0Megan E. Douglas1Simon Driver2Seema Sikka3Rita Hamilton4Chad Swank5Librada Callender6Christa Ochoa7Monica Bennett8Neil Stewart9Gregory V. Chauvin10Barbara O. Rothbaum11Ann Marie Warren12Baylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Corresponding author. Baylor Scott & White Spinal Cord Injury Model System, USA.Baylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USA; Baylor Scott and White Institute for Rehabilitation, Dallas, TX, USABaylor Scott & White Spinal Cord Injury Model System, USA; Emory University School of Medicine, USABaylor Scott & White Spinal Cord Injury Model System, USA; Baylor Scott and White Research Institute, Dallas, TX, USABackground: Scant research has focused on posttraumatic stress disorder (PTSD) in the SCI population, despite high prevalence estimates. Fortunately, prolonged exposure therapy (PE) is a well-researched and highly effective treatment for PTSD. Our recent clinical trial showed that standard 12-session PE was effective for PTSD treatment among inpatients with SCI. Early intervention with brief PE (3-sessions) delivered in the emergency department has also been effective for PTSD prevention, but has not been tested among people post-SCI. Thus, we aim to conduct the first test of the Brief PE intervention to prevent PTSD among patients with SCI. Methods: Adults who have experienced a SCI (N = 200) will be randomly assigned during inpatient rehabilitation to either: (a) 3 60-min sessions of Brief PE (intervention group) or (b) treatment as usual (control group). Results: The primary outcome measure (PTSD symptoms measured by the PSSI-5) and secondary outcome measures (depression, anxiety, pain, quality of life, sleep disturbance, and resilience) will be assessed at baseline, 1-month, 3-months, and 6-months. Hierarchical linear modeling (HLM) will be used to evaluate the effectiveness of the PE intervention on PTSD and secondary outcomes. Descriptive statistics will examine feasibility and will include the number of participants enrolled, the number of sessions completed, fidelity of Brief PE delivery, and average scores for difficulty and helpfulness of the intervention scales for those randomized to intervention. Conclusions: Successful completion of this study will provide an evidence-based program to alleviate posttraumatic distress post spinal cord injury and prevent long-term development of PTSD.http://www.sciencedirect.com/science/article/pii/S2451865422001478Post traumatic stress disorderSpinal cord injuriesSecondary preventionClinical trial protocolBrief psychotherapy |
| spellingShingle | Mark B. Powers Megan E. Douglas Simon Driver Seema Sikka Rita Hamilton Chad Swank Librada Callender Christa Ochoa Monica Bennett Neil Stewart Gregory V. Chauvin Barbara O. Rothbaum Ann Marie Warren Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) Contemporary Clinical Trials Communications Post traumatic stress disorder Spinal cord injuries Secondary prevention Clinical trial protocol Brief psychotherapy |
| title | Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) |
| title_full | Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) |
| title_fullStr | Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) |
| title_full_unstemmed | Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) |
| title_short | Prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury: Study protocol for a randomized controlled trial of Brief Prolonged Exposure Therapy (Brief PE) |
| title_sort | prevention of posttraumatic stress during inpatient rehabilitation post spinal cord injury study protocol for a randomized controlled trial of brief prolonged exposure therapy brief pe |
| topic | Post traumatic stress disorder Spinal cord injuries Secondary prevention Clinical trial protocol Brief psychotherapy |
| url | http://www.sciencedirect.com/science/article/pii/S2451865422001478 |
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