Association between frailty and depression among hemodialysis patients: a cross-sectional study
ABSTRACT BACKGROUND: Frailty is consensually understood to be a clinical syndrome in which minimal stressors can lead to negative outcomes such as hospitalization, early institutionalization, falls, functional loss and death. Frailty is more prevalent among patients with chronic kidney disease (CKD...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
2022-04-01
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802022005007208&tlng=en |
| _version_ | 1828533006664466432 |
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| author | Diana Gabriela Mendes dos Santos Layana Giselly Silva Ferreira Joice Marques Pallone Ana Carolina Ottaviani Ariene Angelini Santos-Orlandi Sofia Cristina Iost Pavarini Marisa Silvana Zazzetta Fabiana de Souza Orlandi |
| author_facet | Diana Gabriela Mendes dos Santos Layana Giselly Silva Ferreira Joice Marques Pallone Ana Carolina Ottaviani Ariene Angelini Santos-Orlandi Sofia Cristina Iost Pavarini Marisa Silvana Zazzetta Fabiana de Souza Orlandi |
| author_sort | Diana Gabriela Mendes dos Santos |
| collection | DOAJ |
| description | ABSTRACT BACKGROUND: Frailty is consensually understood to be a clinical syndrome in which minimal stressors can lead to negative outcomes such as hospitalization, early institutionalization, falls, functional loss and death. Frailty is more prevalent among patients with chronic kidney disease (CKD), and those on dialysis are the frailest. Depression contributes towards putting patients with CKD into the frailty cycle. OBJECTIVE: To assess frailty and its relationship with depression among patients with CKD undergoing hemodialysis. DESIGN AND SETTING: Observational and quantitative cross-sectional study conducted in a renal therapy unit, located in the interior of the state of São Paulo, Brazil. METHODS: This investigation took place in 2019, among 80 patients. The following instruments were applied: a sociodemographic, economic and health condition characterization and the Subjective Frailty Assessment (SFA) and Patient Health Questionnaire-9 (PHQ-9). RESULTS: Among the patients, there was higher prevalence of females, individuals with a steady partner and retirees, and their mean age was 59.63 (± 15.14) years. There was high prevalence of physical frailty (73.8%) and depression (93.7%). Depression was associated with frailty, such that patients with depression were 9.8 times more likely to be frail than were patients without depression (odds ratio, OR = 9.80; 95% confidence interval, CI, 1.93-49.79). CONCLUSION: Based on the proposed objective and the results achieved, it can be concluded that depression was associated with the presence of frailty among patients with CKD on hemodialysis. |
| first_indexed | 2024-12-11T23:02:17Z |
| format | Article |
| id | doaj.art-c1fde05c31bd4024939acfb97cf39028 |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-12-11T23:02:17Z |
| publishDate | 2022-04-01 |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-c1fde05c31bd4024939acfb97cf390282022-12-22T00:47:03ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602022-04-0110.1590/1516-3180.2021.0556.r1.14092021Association between frailty and depression among hemodialysis patients: a cross-sectional studyDiana Gabriela Mendes dos Santoshttps://orcid.org/0000-0003-1572-5322Layana Giselly Silva Ferreirahttps://orcid.org/0000-0002-6471-9511Joice Marques Pallonehttps://orcid.org/0000-0003-4955-6547Ana Carolina Ottavianihttps://orcid.org/0000-0003-4037-4587Ariene Angelini Santos-Orlandihttps://orcid.org/0000-0002-3112-495XSofia Cristina Iost Pavarinihttps://orcid.org/0000-0001-9359-8600Marisa Silvana Zazzettahttps://orcid.org/0000-0001-6544-767XFabiana de Souza Orlandihttps://orcid.org/0000-0002-5714-6890ABSTRACT BACKGROUND: Frailty is consensually understood to be a clinical syndrome in which minimal stressors can lead to negative outcomes such as hospitalization, early institutionalization, falls, functional loss and death. Frailty is more prevalent among patients with chronic kidney disease (CKD), and those on dialysis are the frailest. Depression contributes towards putting patients with CKD into the frailty cycle. OBJECTIVE: To assess frailty and its relationship with depression among patients with CKD undergoing hemodialysis. DESIGN AND SETTING: Observational and quantitative cross-sectional study conducted in a renal therapy unit, located in the interior of the state of São Paulo, Brazil. METHODS: This investigation took place in 2019, among 80 patients. The following instruments were applied: a sociodemographic, economic and health condition characterization and the Subjective Frailty Assessment (SFA) and Patient Health Questionnaire-9 (PHQ-9). RESULTS: Among the patients, there was higher prevalence of females, individuals with a steady partner and retirees, and their mean age was 59.63 (± 15.14) years. There was high prevalence of physical frailty (73.8%) and depression (93.7%). Depression was associated with frailty, such that patients with depression were 9.8 times more likely to be frail than were patients without depression (odds ratio, OR = 9.80; 95% confidence interval, CI, 1.93-49.79). CONCLUSION: Based on the proposed objective and the results achieved, it can be concluded that depression was associated with the presence of frailty among patients with CKD on hemodialysis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802022005007208&tlng=enFrailtyRenal insufficiency, chronicDepressionDialysisKidney diseaseFrailty syndrome |
| spellingShingle | Diana Gabriela Mendes dos Santos Layana Giselly Silva Ferreira Joice Marques Pallone Ana Carolina Ottaviani Ariene Angelini Santos-Orlandi Sofia Cristina Iost Pavarini Marisa Silvana Zazzetta Fabiana de Souza Orlandi Association between frailty and depression among hemodialysis patients: a cross-sectional study São Paulo Medical Journal Frailty Renal insufficiency, chronic Depression Dialysis Kidney disease Frailty syndrome |
| title | Association between frailty and depression among hemodialysis patients: a cross-sectional study |
| title_full | Association between frailty and depression among hemodialysis patients: a cross-sectional study |
| title_fullStr | Association between frailty and depression among hemodialysis patients: a cross-sectional study |
| title_full_unstemmed | Association between frailty and depression among hemodialysis patients: a cross-sectional study |
| title_short | Association between frailty and depression among hemodialysis patients: a cross-sectional study |
| title_sort | association between frailty and depression among hemodialysis patients a cross sectional study |
| topic | Frailty Renal insufficiency, chronic Depression Dialysis Kidney disease Frailty syndrome |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802022005007208&tlng=en |
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