Structural and biophysical characterization of the type VII collagen vWFA2 subdomain leads to identification of two binding sites

Structural and biophysical characterization of the type VII collagen vWFA2 subdomain leads to identification of two binding sites

Type VII collagen is an extracellular matrix protein, which is important for skin stability; however, detailed information at the molecular level is scarce. The second vWFA (von Willebrand factor type A) domain of type VII collagen mediates important interactions, and immunization of mice induces sk...

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Bibliographic Details
Main Authors: Jan M. Gebauer, Florian Flachsenberg, Cordula Windler, Barbara Richer, Ulrich Baumann, Karsten Seeger
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:FEBS Open Bio
Subjects:
epidermolysis bullosa acquisita
integrin binding
laminin‐332
structure
type VII collagen
vWFA2
Online Access:https://doi.org/10.1002/2211-5463.12807

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