Endothelial Cell Activation by SARS-CoV-2 Spike S1 Protein: A Crosstalk between Endothelium and Innate Immune Cells
Background. Emerging evidences suggest that in severe COVID-19, multi-organ failure is associated with a hyperinflammatory state (the so-called “cytokine storm”) in combination with the development of a prothrombotic state. The central role of endothelial dysfunction in the pathogenesis of the disea...
Main Authors: | Bianca Maria Rotoli, Amelia Barilli, Rossana Visigalli, Francesca Ferrari, Valeria Dall’Asta |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/9/9/1220 |
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