Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic?
The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and associated development of clinical symptoms of COVID-19 have presented an enormous global impact on our health care systems, public health and economy. To date several observational epidemiological studies co...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.888168/full |
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| author | Daniela Briceno Noriega Huub F. J. Savelkoul |
| author_facet | Daniela Briceno Noriega Huub F. J. Savelkoul |
| author_sort | Daniela Briceno Noriega |
| collection | DOAJ |
| description | The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and associated development of clinical symptoms of COVID-19 have presented an enormous global impact on our health care systems, public health and economy. To date several observational epidemiological studies consistently found that vitamin D deficiency, measured as low levels of circulating 25-hydroxyvitamin D, is associated with cardiovascular diseases, diabetes, certain cancers, autoimmune diseases and many infectious diseases, including acute respiratory infections. Since vitamin D is not merely immunosuppressive but also acts as an immunomodulator in tolerance and homeostasis, many experts have considered a role of vitamin D in the prevalence and severity of immune mediated inflammatory diseases, such as SARS-CoV-2, adding to the evidence of the importance of vitamin D in the immune response against viral respiratory infections and reinforcing the need for targeted vitamin D supplementation, with a focus on high-risk populations and a high-dose supplementation treatment for COVID-19 hospitalized patients. The expected transition to endemicity of SARS-CoV-2 even further corroborates as a potential of vitamin D as an potential mitigation tool for the prevention of COVID-19. The aim of this paper is to analyse the current evidence regarding vitamin D and present a hypothesis of its potential role in the current COVID-19 pandemic and in the future as a potential preventive measurement in public health. |
| first_indexed | 2024-04-12T18:09:28Z |
| format | Article |
| id | doaj.art-c209fddd9ba84f7998e0bad11511ec90 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-12T18:09:28Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-c209fddd9ba84f7998e0bad11511ec902022-12-22T03:21:52ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-06-011010.3389/fpubh.2022.888168888168Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic?Daniela Briceno NoriegaHuub F. J. SavelkoulThe impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic and associated development of clinical symptoms of COVID-19 have presented an enormous global impact on our health care systems, public health and economy. To date several observational epidemiological studies consistently found that vitamin D deficiency, measured as low levels of circulating 25-hydroxyvitamin D, is associated with cardiovascular diseases, diabetes, certain cancers, autoimmune diseases and many infectious diseases, including acute respiratory infections. Since vitamin D is not merely immunosuppressive but also acts as an immunomodulator in tolerance and homeostasis, many experts have considered a role of vitamin D in the prevalence and severity of immune mediated inflammatory diseases, such as SARS-CoV-2, adding to the evidence of the importance of vitamin D in the immune response against viral respiratory infections and reinforcing the need for targeted vitamin D supplementation, with a focus on high-risk populations and a high-dose supplementation treatment for COVID-19 hospitalized patients. The expected transition to endemicity of SARS-CoV-2 even further corroborates as a potential of vitamin D as an potential mitigation tool for the prevention of COVID-19. The aim of this paper is to analyse the current evidence regarding vitamin D and present a hypothesis of its potential role in the current COVID-19 pandemic and in the future as a potential preventive measurement in public health.https://www.frontiersin.org/articles/10.3389/fpubh.2022.888168/fullvitamin DCOVID-19SARS-CoV-2vitamin D supplementationendemicvitamin D deficiency |
| spellingShingle | Daniela Briceno Noriega Huub F. J. Savelkoul Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? Frontiers in Public Health vitamin D COVID-19 SARS-CoV-2 vitamin D supplementation endemic vitamin D deficiency |
| title | Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? |
| title_full | Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? |
| title_fullStr | Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? |
| title_full_unstemmed | Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? |
| title_short | Vitamin D: A Potential Mitigation Tool for the Endemic Stage of the COVID-19 Pandemic? |
| title_sort | vitamin d a potential mitigation tool for the endemic stage of the covid 19 pandemic |
| topic | vitamin D COVID-19 SARS-CoV-2 vitamin D supplementation endemic vitamin D deficiency |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.888168/full |
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