Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome

We presently report the case of hantavirus infection in a 45-year-old male who was hospitalized to our clinic of infectious diseases, with fever, myalgia, vomiting, nausea, headache, and abdominal pain. The physical findings included hepatomegaly, splenomegaly, rash, and conjunctival injection. Eigh...

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Main Authors: Ermira Muco, Amela Hasa, Arben Rroji, Arta Kushi, Edmond Puca, Dhimiter Kraja
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2020/1017689
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author Ermira Muco
Amela Hasa
Arben Rroji
Arta Kushi
Edmond Puca
Dhimiter Kraja
author_facet Ermira Muco
Amela Hasa
Arben Rroji
Arta Kushi
Edmond Puca
Dhimiter Kraja
author_sort Ermira Muco
collection DOAJ
description We presently report the case of hantavirus infection in a 45-year-old male who was hospitalized to our clinic of infectious diseases, with fever, myalgia, vomiting, nausea, headache, and abdominal pain. The physical findings included hepatomegaly, splenomegaly, rash, and conjunctival injection. Eight days before the start of complaints, the patient has cut trees in the mountain. An acute renal failure was observed with an oliguria and an increase of serum creatinine and blood urea nitrogen. Urinalysis shows albuminuria and hematuria. Elevations of amylase, lipase, and liver enzymes levels, low serum albumin level, and thrombocytopenia were observed. A positive ELISA test for hantavirus IgM/IgG antibodies confirmed hemorrhagic fever with renal syndrome. On the third day of hospitalization, the patient had seizures. The unenhanced head computed tomography (CT) performed after seizures showed subcortical bilateral hypodensities within frontal, parietal, and occipital regions corresponding to areas of increased signal intensity in magnetic resonance imaging (MRI) associated with cerebral edema in posterior reversible encephalopathy syndrome (PRES). The treatment consisted of supportive therapy. The patient underwent another head MRI with contrast enhancement after 2 months, which resulted normal.
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spelling doaj.art-c20a4d2ff7b3492a8e4ba4fa59df9d9a2024-11-02T05:18:03ZengHindawi LimitedCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/10176891017689Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal SyndromeErmira Muco0Amela Hasa1Arben Rroji2Arta Kushi3Edmond Puca4Dhimiter Kraja5Department of Infectious Diseases, Hospital University Center “Mother Theresa”, Tirana, AlbaniaDepartment of Imaging Sciences, Hospital University Center “Mother Theresa”, Tirana, AlbaniaDepartment of Imaging Sciences, Hospital University Center “Mother Theresa”, Tirana, AlbaniaDepartment of Infectious Diseases, Hospital University Center “Mother Theresa”, Tirana, AlbaniaDepartment of Infectious Diseases, Hospital University Center “Mother Theresa”, Tirana, AlbaniaDepartment of Infectious Diseases, Hospital University Center “Mother Theresa”, Tirana, AlbaniaWe presently report the case of hantavirus infection in a 45-year-old male who was hospitalized to our clinic of infectious diseases, with fever, myalgia, vomiting, nausea, headache, and abdominal pain. The physical findings included hepatomegaly, splenomegaly, rash, and conjunctival injection. Eight days before the start of complaints, the patient has cut trees in the mountain. An acute renal failure was observed with an oliguria and an increase of serum creatinine and blood urea nitrogen. Urinalysis shows albuminuria and hematuria. Elevations of amylase, lipase, and liver enzymes levels, low serum albumin level, and thrombocytopenia were observed. A positive ELISA test for hantavirus IgM/IgG antibodies confirmed hemorrhagic fever with renal syndrome. On the third day of hospitalization, the patient had seizures. The unenhanced head computed tomography (CT) performed after seizures showed subcortical bilateral hypodensities within frontal, parietal, and occipital regions corresponding to areas of increased signal intensity in magnetic resonance imaging (MRI) associated with cerebral edema in posterior reversible encephalopathy syndrome (PRES). The treatment consisted of supportive therapy. The patient underwent another head MRI with contrast enhancement after 2 months, which resulted normal.http://dx.doi.org/10.1155/2020/1017689
spellingShingle Ermira Muco
Amela Hasa
Arben Rroji
Arta Kushi
Edmond Puca
Dhimiter Kraja
Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
Case Reports in Infectious Diseases
title Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
title_full Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
title_fullStr Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
title_full_unstemmed Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
title_short Posterior Reversible Encephalopathy Syndrome in a Patient with Hemorrhagic Fever with Renal Syndrome
title_sort posterior reversible encephalopathy syndrome in a patient with hemorrhagic fever with renal syndrome
url http://dx.doi.org/10.1155/2020/1017689
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