The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions
Heavy metal stress (HMS) is one of the most destructive abiotic stresses which seriously affects the growth and development of plants. Recent studies have shown significant progress in understanding the molecular mechanisms underlying plant tolerance to HMS. In general, three core signals are involv...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-12-01
|
| Series: | Membranes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0375/11/12/984 |
| _version_ | 1797502607875375104 |
|---|---|
| author | Danxia Wu Muhammad Saleem Tengbing He Guandi He |
| author_facet | Danxia Wu Muhammad Saleem Tengbing He Guandi He |
| author_sort | Danxia Wu |
| collection | DOAJ |
| description | Heavy metal stress (HMS) is one of the most destructive abiotic stresses which seriously affects the growth and development of plants. Recent studies have shown significant progress in understanding the molecular mechanisms underlying plant tolerance to HMS. In general, three core signals are involved in plants’ responses to HMS; these are mitogen-activated protein kinase (MAPK), calcium, and hormonal (abscisic acid) signals. In addition to these signal components, other regulatory factors, such as microRNAs and membrane proteins, also play an important role in regulating HMS responses in plants. Membrane proteins interact with the highly complex and heterogeneous lipids in the plant cell environment. The function of membrane proteins is affected by the interactions between lipids and lipid-membrane proteins. Our review findings also indicate the possibility of membrane protein-lipid-metal ion interactions in regulating metal homeostasis in plant cells. In this review, we investigated the role of membrane proteins with specific substrate recognition in regulating cell metal homeostasis. The understanding of the possible interaction networks and upstream and downstream pathways is developed. In addition, possible interactions between membrane proteins, metal ions, and lipids are discussed to provide new ideas for studying metal homeostasis in plant cells. |
| first_indexed | 2024-03-10T03:35:33Z |
| format | Article |
| id | doaj.art-c20cfd35702f4109973398df6600552d |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-10T03:35:33Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-c20cfd35702f4109973398df6600552d2023-11-23T09:30:49ZengMDPI AGMembranes2077-03752021-12-01111298410.3390/membranes11120984The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal IonsDanxia Wu0Muhammad Saleem1Tengbing He2Guandi He3College of Agricultural, Guizhou University, Guiyang 550025, ChinaDepartment of Biological Sciences, Alabama State University, Montgomery, AL 36104, USACollege of Agricultural, Guizhou University, Guiyang 550025, ChinaCollege of Agricultural, Guizhou University, Guiyang 550025, ChinaHeavy metal stress (HMS) is one of the most destructive abiotic stresses which seriously affects the growth and development of plants. Recent studies have shown significant progress in understanding the molecular mechanisms underlying plant tolerance to HMS. In general, three core signals are involved in plants’ responses to HMS; these are mitogen-activated protein kinase (MAPK), calcium, and hormonal (abscisic acid) signals. In addition to these signal components, other regulatory factors, such as microRNAs and membrane proteins, also play an important role in regulating HMS responses in plants. Membrane proteins interact with the highly complex and heterogeneous lipids in the plant cell environment. The function of membrane proteins is affected by the interactions between lipids and lipid-membrane proteins. Our review findings also indicate the possibility of membrane protein-lipid-metal ion interactions in regulating metal homeostasis in plant cells. In this review, we investigated the role of membrane proteins with specific substrate recognition in regulating cell metal homeostasis. The understanding of the possible interaction networks and upstream and downstream pathways is developed. In addition, possible interactions between membrane proteins, metal ions, and lipids are discussed to provide new ideas for studying metal homeostasis in plant cells.https://www.mdpi.com/2077-0375/11/12/984specific transmembrane proteinsprotein-lipid interactionsplant metal homeostasis |
| spellingShingle | Danxia Wu Muhammad Saleem Tengbing He Guandi He The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions Membranes specific transmembrane proteins protein-lipid interactions plant metal homeostasis |
| title | The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions |
| title_full | The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions |
| title_fullStr | The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions |
| title_full_unstemmed | The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions |
| title_short | The Mechanism of Metal Homeostasis in Plants: A New View on the Synergistic Regulation Pathway of Membrane Proteins, Lipids and Metal Ions |
| title_sort | mechanism of metal homeostasis in plants a new view on the synergistic regulation pathway of membrane proteins lipids and metal ions |
| topic | specific transmembrane proteins protein-lipid interactions plant metal homeostasis |
| url | https://www.mdpi.com/2077-0375/11/12/984 |
| work_keys_str_mv | AT danxiawu themechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT muhammadsaleem themechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT tengbinghe themechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT guandihe themechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT danxiawu mechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT muhammadsaleem mechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT tengbinghe mechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions AT guandihe mechanismofmetalhomeostasisinplantsanewviewonthesynergisticregulationpathwayofmembraneproteinslipidsandmetalions |