Functional cross talk between CXCR4 and PDGFR on glioblastoma cells is essential for migration.

Functional cross talk between CXCR4 and PDGFR on glioblastoma cells is essential for migration.

Glioblastoma (GBM) is the most common and aggressive form of brain tumor, characterized by high migratory behavior and infiltration in brain parenchyma which render classic therapeutic approach ineffective. The migratory behaviour of GBM cells could be conditioned by a number of tissue- and glioma-d...

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Bibliographic Details
Main Authors: Miriam Sciaccaluga, Giuseppina D'Alessandro, Francesca Pagani, Giuseppina Ferrara, Nadia Lopez, Tracy Warr, Paolo Gorello, Alessandra Porzia, Fabrizio Mainiero, Antonio Santoro, Vincenzo Esposito, Giampaolo Cantore, Emilia Castigli, Cristina Limatola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759384?pdf=render

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