Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer

Abstract Background Enhancer dysregulation is one of the important features for cancer cells. Enhancers enriched with H3K4me3 have been implicated to play important roles in cancer. However, their detailed features and regulatory mechanisms have not been well characterized. Results Here, we profile...

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Bibliographic Details
Main Authors: Xiang Lin, Ji-Dong Chen, Chen-Yu Wang, Zhen Cai, Rui Zhan, Chen Yang, La-Ying Zhang, Lian-Yun Li, Yong Xiao, Ming-Kai Chen, Min Wu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-03108-3