Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome

Complex regional pain syndrome (CRPS) is a variety of painful conditions following injury which appears regionally having a distal predominance of abnormal findings. This study, evaluate the use of phentolamine for sympathetic block and regional anesthesia in treatment of CRPS related pain. In this...

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Main Authors: Hooshang Shahriyari, Sirous Momenzadeh, Kambiz Bagherzadi, Asadollah Saadat Niaki, Mehrdad Mokarram Dori
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2011-08-01
Series:Acta Medica Iranica
Subjects:
Online Access:http://journals.tums.ac.ir/upload_files/pdf/19354.pdf
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author Hooshang Shahriyari
Sirous Momenzadeh
Kambiz Bagherzadi
Asadollah Saadat Niaki
Mehrdad Mokarram Dori
author_facet Hooshang Shahriyari
Sirous Momenzadeh
Kambiz Bagherzadi
Asadollah Saadat Niaki
Mehrdad Mokarram Dori
author_sort Hooshang Shahriyari
collection DOAJ
description Complex regional pain syndrome (CRPS) is a variety of painful conditions following injury which appears regionally having a distal predominance of abnormal findings. This study, evaluate the use of phentolamine for sympathetic block and regional anesthesia in treatment of CRPS related pain. In this study, 68 patients with CRPS who were referred to pain clinics of Imam Hossein and Akhtar Hospitals and Gandy Center of Surgery between 2003-2008 were evaluated. Forty three of 87 patients finally undertaken intravenous regional sympatholytic block according to therapeutic protocol. 37 patients (86%) received one block, 2 of them (4.75%) received 2 repetitions of blocks and finally repeated block for three times occurred in 4 patients (9.3%). A week after block pain relief outcomes was recorded as following; excellent in 7 patients (16.3%), good in the 32 patients (74.4%) and moderate in the 4 patients (9.3%). After a month, 8 patients (18.5%) showed excellent relief and it was good and moderate in 32 (78%) and one case (2.4%), respectively. Pain relief after three months was excellent, good and moderate in the 13 patients (31.7%), 25 patients (61%) and 3 patients (7.3%), respectively. In this study level of pain relief was significant in various intervals and it showed significant difference in relief three months after block (P=0.04). CRPS due to SMP(sympathetically maintained pain) is thought to be alleviated by phentolamine. Intravenous phentolamine infusion is potentially a new significant option for the therapy of CRPS.
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spelling doaj.art-c20e7d96766944f38d9ce9e00629fe772022-12-22T01:27:48ZengTehran University of Medical SciencesActa Medica Iranica0044-60252011-08-01498523526Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain SyndromeHooshang ShahriyariSirous MomenzadehKambiz BagherzadiAsadollah Saadat NiakiMehrdad Mokarram DoriComplex regional pain syndrome (CRPS) is a variety of painful conditions following injury which appears regionally having a distal predominance of abnormal findings. This study, evaluate the use of phentolamine for sympathetic block and regional anesthesia in treatment of CRPS related pain. In this study, 68 patients with CRPS who were referred to pain clinics of Imam Hossein and Akhtar Hospitals and Gandy Center of Surgery between 2003-2008 were evaluated. Forty three of 87 patients finally undertaken intravenous regional sympatholytic block according to therapeutic protocol. 37 patients (86%) received one block, 2 of them (4.75%) received 2 repetitions of blocks and finally repeated block for three times occurred in 4 patients (9.3%). A week after block pain relief outcomes was recorded as following; excellent in 7 patients (16.3%), good in the 32 patients (74.4%) and moderate in the 4 patients (9.3%). After a month, 8 patients (18.5%) showed excellent relief and it was good and moderate in 32 (78%) and one case (2.4%), respectively. Pain relief after three months was excellent, good and moderate in the 13 patients (31.7%), 25 patients (61%) and 3 patients (7.3%), respectively. In this study level of pain relief was significant in various intervals and it showed significant difference in relief three months after block (P=0.04). CRPS due to SMP(sympathetically maintained pain) is thought to be alleviated by phentolamine. Intravenous phentolamine infusion is potentially a new significant option for the therapy of CRPS.http://journals.tums.ac.ir/upload_files/pdf/19354.pdfAutonomic Nerve BlockPhentolamineComplex Regional Pain Syndrome
spellingShingle Hooshang Shahriyari
Sirous Momenzadeh
Kambiz Bagherzadi
Asadollah Saadat Niaki
Mehrdad Mokarram Dori
Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
Acta Medica Iranica
Autonomic Nerve Block
Phentolamine
Complex Regional Pain Syndrome
title Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
title_full Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
title_fullStr Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
title_full_unstemmed Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
title_short Intravenous Regional Block with Phentolamine in the Treatment of Complex Regional Pain Syndrome
title_sort intravenous regional block with phentolamine in the treatment of complex regional pain syndrome
topic Autonomic Nerve Block
Phentolamine
Complex Regional Pain Syndrome
url http://journals.tums.ac.ir/upload_files/pdf/19354.pdf
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AT kambizbagherzadi intravenousregionalblockwithphentolamineinthetreatmentofcomplexregionalpainsyndrome
AT asadollahsaadatniaki intravenousregionalblockwithphentolamineinthetreatmentofcomplexregionalpainsyndrome
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