Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation

Manuka honey activates the aryl hydrocarbon receptor: Implications for skin inflammation

Manuka honey (MH) is a complex nutritional material with antimicrobial, antioxidant and anti-inflammatory activity. We have previously shown that MH down regulates IL-4-induced CCL26 expression in immortalized keratinocytes. As MH contains potential ligands of the Aryl Hydrocarbon Receptor (AHR), a...

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Bibliographic Details
Main Authors: Abdullah A. Alangari, Matin D. Ashoori, Wisam Alwan, Hannah R. Dawe, Brigitta Stockinger, Jonathan N. Barker, Emma Wincent, Paola Di Meglio
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Pharmacological Research
Subjects:
Aryl hydrocarbon receptor (AHR)
CCL26
Filaggrin
IL-4
Manuka honey
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823002049

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