Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.

Genetic variation in the TP53 pathway and bladder cancer risk. a comprehensive analysis.

Germline variants in TP63 have been consistently associated with several tumors, including bladder cancer, indicating the importance of TP53 pathway in cancer genetic susceptibility. However, variants in other related genes, including TP53 rs1042522 (Arg72Pro), still present controversial results. W...

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Detalles Bibliográficos
Main Authors: Silvia Pineda, Roger L Milne, M Luz Calle, Nathaniel Rothman, Evangelina López de Maturana, Jesús Herranz, Manolis Kogevinas, Stephen J Chanock, Adonina Tardón, Mirari Márquez, Lin T Guey, Montserrat García-Closas, Josep Lloreta, Erin Baum, Anna González-Neira, Alfredo Carrato, Arcadi Navarro, Debra T Silverman, Francisco X Real, Núria Malats
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4018346?pdf=render

Internet

http://europepmc.org/articles/PMC4018346?pdf=render

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