Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV

Kaposi Sarcoma (KS) is an angio-proliferative mesenchymal neoplasm that typically affects the skin. In the setting of AIDS, it is usually disseminated, commonly involving noncutaneous sites like oral cavity, lymph nodes, pulmonary, and gastrointestinal systems. Musculoskeletal system involvement by...

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Main Authors: Swati Sharma, MD, Chandana Kurra, MD, Marsela Hyska-Campbell, DO, Kristin Taylor, MD, Mauricio Hernandez, PhD, Christine Palma, DPM, Ahmad Alkhasawneh, MD, Paul Wasserman, DO
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Radiology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043319303140
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author Swati Sharma, MD
Chandana Kurra, MD
Marsela Hyska-Campbell, DO
Kristin Taylor, MD
Mauricio Hernandez, PhD
Christine Palma, DPM
Ahmad Alkhasawneh, MD
Paul Wasserman, DO
author_facet Swati Sharma, MD
Chandana Kurra, MD
Marsela Hyska-Campbell, DO
Kristin Taylor, MD
Mauricio Hernandez, PhD
Christine Palma, DPM
Ahmad Alkhasawneh, MD
Paul Wasserman, DO
author_sort Swati Sharma, MD
collection DOAJ
description Kaposi Sarcoma (KS) is an angio-proliferative mesenchymal neoplasm that typically affects the skin. In the setting of AIDS, it is usually disseminated, commonly involving noncutaneous sites like oral cavity, lymph nodes, pulmonary, and gastrointestinal systems. Musculoskeletal system involvement by KS is rare, and when encountered, it typically involves the axial skeleton (vertebrae, ribs, sternum, and pelvis) and/or maxillofacial bones. This report describes an unusual case of a 44-year old patient with HIV, who presented with a foot ulcer that fit the typical clinical features of osteomyelitis until MRI of the foot demonstrated atypical findings that challenged the original clinical diagnosis. This case highlights the role that advanced diagnostic imaging plays in the diagnosis of musculoskeletal Kaposi Sarcoma and serves as a reminder to radiologists to include Kaposi Sarcoma in the differential of multifocal osteolytic lesions in patients with HIV. Keywords: Kaposi Sarcoma, HIV, AIDS, Bone, Foot, Osteomyelitis
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spelling doaj.art-c210dfd8916e4b2dae66e59378e139db2022-12-21T22:20:45ZengElsevierRadiology Case Reports1930-04332019-12-01141214951499Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIVSwati Sharma, MD0Chandana Kurra, MD1Marsela Hyska-Campbell, DO2Kristin Taylor, MD3Mauricio Hernandez, PhD4Christine Palma, DPM5Ahmad Alkhasawneh, MD6Paul Wasserman, DO7Department of Radiology, University of Florida, Jacksonville FL, USA; Corresponding author.Department of Radiology, University of Florida, Jacksonville FL, USADepartment of Radiology, University of Florida, Jacksonville FL, USADepartment of Radiology, University of Florida, Jacksonville FL, USADepartment of Radiology, University of Florida, Jacksonville FL, USADepartment of Podiatry, University of Florida, Jacksonville FL, USADepartment of Pathology, University of Florida, Jacksonville FL, USADepartment of Radiology, University of Florida, Jacksonville FL, USAKaposi Sarcoma (KS) is an angio-proliferative mesenchymal neoplasm that typically affects the skin. In the setting of AIDS, it is usually disseminated, commonly involving noncutaneous sites like oral cavity, lymph nodes, pulmonary, and gastrointestinal systems. Musculoskeletal system involvement by KS is rare, and when encountered, it typically involves the axial skeleton (vertebrae, ribs, sternum, and pelvis) and/or maxillofacial bones. This report describes an unusual case of a 44-year old patient with HIV, who presented with a foot ulcer that fit the typical clinical features of osteomyelitis until MRI of the foot demonstrated atypical findings that challenged the original clinical diagnosis. This case highlights the role that advanced diagnostic imaging plays in the diagnosis of musculoskeletal Kaposi Sarcoma and serves as a reminder to radiologists to include Kaposi Sarcoma in the differential of multifocal osteolytic lesions in patients with HIV. Keywords: Kaposi Sarcoma, HIV, AIDS, Bone, Foot, Osteomyelitishttp://www.sciencedirect.com/science/article/pii/S1930043319303140
spellingShingle Swati Sharma, MD
Chandana Kurra, MD
Marsela Hyska-Campbell, DO
Kristin Taylor, MD
Mauricio Hernandez, PhD
Christine Palma, DPM
Ahmad Alkhasawneh, MD
Paul Wasserman, DO
Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
Radiology Case Reports
title Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
title_full Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
title_fullStr Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
title_full_unstemmed Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
title_short Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV
title_sort kaposi sarcoma mimicking pedal osteomyelitis in a patient with hiv
url http://www.sciencedirect.com/science/article/pii/S1930043319303140
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