Prefrontal damage in childhood and changes in the development of personality: A case report
ABSTRACT Frontal lobe lesions are associated with behavioral abnormalities and executive dysfunction. When these lesions occur early in life, the symptoms are even more severe as the anatomical and functional substrates underlying personality and behavior are damaged, distorting normal modulation by...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000100132&lng=en&tlng=en |
| _version_ | 1819055616697565184 |
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| author | Valéria Santoro Bahia Leonel Tadao Takada Leonardo Caixeta Leandro Tavares Lucato Claudia Sellitto Porto Ricardo Nitrini |
| author_facet | Valéria Santoro Bahia Leonel Tadao Takada Leonardo Caixeta Leandro Tavares Lucato Claudia Sellitto Porto Ricardo Nitrini |
| author_sort | Valéria Santoro Bahia |
| collection | DOAJ |
| description | ABSTRACT Frontal lobe lesions are associated with behavioral abnormalities and executive dysfunction. When these lesions occur early in life, the symptoms are even more severe as the anatomical and functional substrates underlying personality and behavior are damaged, distorting normal modulation by interaction with the psychosocial environment. We present a case of a 40-year-old man who suffered a frontal lobe lesion at the age of nine years and developed impulsivity, disinhibition and inappropriate behaviors while showing some preservation of insight. Brain MRI revealed lesions to bilateral orbitofrontal cortex, ventromedial prefrontal cortex, anterior cingulate gyri and genu of the corpus callosum , which were more extensive on the right side. The right prefrontal dorsolateral cortex was severely damaged, whereas the right ventrolateral prefrontal cortex was spared. We will discuss the correlation of the damaged pre frontal regions with the symptoms presented by the patient. |
| first_indexed | 2024-12-21T13:10:21Z |
| format | Article |
| id | doaj.art-c212908f9da2432a9c1fdbe1d5cc3359 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-12-21T13:10:21Z |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-c212908f9da2432a9c1fdbe1d5cc33592022-12-21T19:02:55ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57647113213510.1590/S1980-57642013DN70100019S1980-57642013000100132Prefrontal damage in childhood and changes in the development of personality: A case reportValéria Santoro BahiaLeonel Tadao TakadaLeonardo CaixetaLeandro Tavares LucatoClaudia Sellitto PortoRicardo NitriniABSTRACT Frontal lobe lesions are associated with behavioral abnormalities and executive dysfunction. When these lesions occur early in life, the symptoms are even more severe as the anatomical and functional substrates underlying personality and behavior are damaged, distorting normal modulation by interaction with the psychosocial environment. We present a case of a 40-year-old man who suffered a frontal lobe lesion at the age of nine years and developed impulsivity, disinhibition and inappropriate behaviors while showing some preservation of insight. Brain MRI revealed lesions to bilateral orbitofrontal cortex, ventromedial prefrontal cortex, anterior cingulate gyri and genu of the corpus callosum , which were more extensive on the right side. The right prefrontal dorsolateral cortex was severely damaged, whereas the right ventrolateral prefrontal cortex was spared. We will discuss the correlation of the damaged pre frontal regions with the symptoms presented by the patient.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000100132&lng=en&tlng=entraumatic brain injuryneuropsychologyfrontal lobesocial behavior |
| spellingShingle | Valéria Santoro Bahia Leonel Tadao Takada Leonardo Caixeta Leandro Tavares Lucato Claudia Sellitto Porto Ricardo Nitrini Prefrontal damage in childhood and changes in the development of personality: A case report Dementia & Neuropsychologia traumatic brain injury neuropsychology frontal lobe social behavior |
| title | Prefrontal damage in childhood and changes in the development of personality: A case report |
| title_full | Prefrontal damage in childhood and changes in the development of personality: A case report |
| title_fullStr | Prefrontal damage in childhood and changes in the development of personality: A case report |
| title_full_unstemmed | Prefrontal damage in childhood and changes in the development of personality: A case report |
| title_short | Prefrontal damage in childhood and changes in the development of personality: A case report |
| title_sort | prefrontal damage in childhood and changes in the development of personality a case report |
| topic | traumatic brain injury neuropsychology frontal lobe social behavior |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000100132&lng=en&tlng=en |
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