Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study
A new series of 4,6-disubstituted 2-(4-(dimethylamino)styryl)quinoline 4a,b–9a,b was synthesized by the reaction of 2-(4-(dimethylamino)styryl)-6-substituted quinoline-4-carboxylic acids 3a,b with thiosemicarbazide, p-hydroxybenzaldehyde, ethylcyanoacetate, and 2,4-pentandione. In addition, the anti...
| Main Authors: | , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Taylor & Francis Group
2018-01-01
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| 叢編: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| 主題: | |
| 在線閱讀: | http://dx.doi.org/10.1080/14756366.2017.1407926 |