Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child
Pilocytic astrocytomas correspond to lowgrade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases? We present a case report of a 3-year-old child with a pilocytic a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-03-01
|
| Series: | Clinics and Practice |
| Subjects: | |
| Online Access: | https://www.clinicsandpractice.org/index.php/cp/article/view/813 |
| _version_ | 1811186107768897536 |
|---|---|
| author | Ameer Alyeldien Sarah Teuber-Hanselmann Azad Cheko Tanja Höll Martin Scholz Athanasios K. Petridis |
| author_facet | Ameer Alyeldien Sarah Teuber-Hanselmann Azad Cheko Tanja Höll Martin Scholz Athanasios K. Petridis |
| author_sort | Ameer Alyeldien |
| collection | DOAJ |
| description | Pilocytic astrocytomas correspond to lowgrade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases? We present a case report of a 3-year-old child with a pilocytic astrocytoma of the optic chiasm with leptomeningeal dissemination of the spinal meninges. Partial resection of the cerebral tumor has been performed. Since the leptomeningeal dissemination was seen all over the spinal meninges, the child did not undergo further surgical treatment. A wait and watch strategy were followed. Chemotherapy was initiated, if a 25% tumor growth was seen. Leptomeningeal dissemination of a pilocytic astrocytoma is seen so infrequently that no standard therapy is established. Since these metastases may occur even up to 2 decades after primary tumor resection, long-term follow- up is indicated. In case of spinal metastases, surgical treatment should be performed if feasible. Otherwise observation should be possessed and/or chemotherapy should be initiated. |
| first_indexed | 2024-04-11T13:40:07Z |
| format | Article |
| id | doaj.art-c216deb09a1f4315863d8d1fb2d69f9a |
| institution | Directory Open Access Journal |
| issn | 2039-7275 2039-7283 |
| language | English |
| last_indexed | 2024-04-11T13:40:07Z |
| publishDate | 2016-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clinics and Practice |
| spelling | doaj.art-c216deb09a1f4315863d8d1fb2d69f9a2022-12-22T04:21:17ZengMDPI AGClinics and Practice2039-72752039-72832016-03-016110.4081/cp.2016.813333Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old childAmeer Alyeldien0Sarah Teuber-Hanselmann1Azad Cheko2Tanja Höll3Martin Scholz4Athanasios K. Petridis5Department of Neurosurgery, Sana Kliniken, DuisburgInstitute of Neuropathology, University of Duisburg-Essen, EssenDepartment of Neurosurgery, Sana Kliniken, DuisburgDepartment of Pediatrics, Sana Kliniken, DuisburgDepartment of Neurosurgery, Sana Kliniken, DuisburgDepartment of Neurosurgery, Heinrich Heine University, DüsseldorfPilocytic astrocytomas correspond to lowgrade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases? We present a case report of a 3-year-old child with a pilocytic astrocytoma of the optic chiasm with leptomeningeal dissemination of the spinal meninges. Partial resection of the cerebral tumor has been performed. Since the leptomeningeal dissemination was seen all over the spinal meninges, the child did not undergo further surgical treatment. A wait and watch strategy were followed. Chemotherapy was initiated, if a 25% tumor growth was seen. Leptomeningeal dissemination of a pilocytic astrocytoma is seen so infrequently that no standard therapy is established. Since these metastases may occur even up to 2 decades after primary tumor resection, long-term follow- up is indicated. In case of spinal metastases, surgical treatment should be performed if feasible. Otherwise observation should be possessed and/or chemotherapy should be initiated.https://www.clinicsandpractice.org/index.php/cp/article/view/813Pilocytic astrocytomametastasisspinal disseminationoptic chiasm. |
| spellingShingle | Ameer Alyeldien Sarah Teuber-Hanselmann Azad Cheko Tanja Höll Martin Scholz Athanasios K. Petridis Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child Clinics and Practice Pilocytic astrocytoma metastasis spinal dissemination optic chiasm. |
| title | Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child |
| title_full | Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child |
| title_fullStr | Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child |
| title_full_unstemmed | Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child |
| title_short | Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child |
| title_sort | diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3 year old child |
| topic | Pilocytic astrocytoma metastasis spinal dissemination optic chiasm. |
| url | https://www.clinicsandpractice.org/index.php/cp/article/view/813 |
| work_keys_str_mv | AT ameeralyeldien diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild AT sarahteuberhanselmann diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild AT azadcheko diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild AT tanjaholl diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild AT martinscholz diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild AT athanasioskpetridis diffusespinalleptomeningealspreadofapilocyticastrocytomaina3yearoldchild |