Pharmacodynamic Markers for Choline Kinase Down-regulation in Breast Cancer Cells

High levels of choline kinase (ChoK) expression and choline phospholipid metabolites are often associated with malignant transformation, invasion, and metastasis, particularly in breast cancer. These findings have led to the development of novel pharmacologic or gene therapeutic interventions for Ch...

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Bibliographic Details
Main Authors: Sridhar Nimmagadda, Kristine Glunde, Martin G. Pomper, Zaver M. Bhujwalla
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800560

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