Pharmacodynamic Markers for Choline Kinase Down-regulation in Breast Cancer Cells
High levels of choline kinase (ChoK) expression and choline phospholipid metabolites are often associated with malignant transformation, invasion, and metastasis, particularly in breast cancer. These findings have led to the development of novel pharmacologic or gene therapeutic interventions for Ch...
Main Authors: | Sridhar Nimmagadda, Kristine Glunde, Martin G. Pomper, Zaver M. Bhujwalla |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-05-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558609800560 |
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