Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil
Abstract Background Few studies have evaluated the role played by pesticide exposure in the development of Parkinson’s disease (PD) in Brazil. Objective This study aimed to investigate the association between pesticide use and PD hospitalization in Brazilian micro-regions. Method Pesticide expend...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Instituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de Janeiro
2021-12-01
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| Series: | Cadernos de Saúde Coletiva |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1414-462X2021005019204&tlng=pt |
| _version_ | 1798015659092738048 |
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| author | Aline de Souza Espindola Santos Noa Krawczyk Christine Gibson Parks Carmen Froes Ildes Asmus Volney de Magalhães Câmara Jaime Lima Armando Meyer |
| author_facet | Aline de Souza Espindola Santos Noa Krawczyk Christine Gibson Parks Carmen Froes Ildes Asmus Volney de Magalhães Câmara Jaime Lima Armando Meyer |
| author_sort | Aline de Souza Espindola Santos |
| collection | DOAJ |
| description | Abstract Background Few studies have evaluated the role played by pesticide exposure in the development of Parkinson’s disease (PD) in Brazil. Objective This study aimed to investigate the association between pesticide use and PD hospitalization in Brazilian micro-regions. Method Pesticide expenditure per capita in 1985 and PD hospitalization rates (HR) from 1997 to 2007 were calculated for all 552 Brazilian micro-regions. The Spearman's correlation test was used to compare pesticide expenditure and PD HR by sex, age, and urban and non-urban micro-regions. Micro-regions were grouped according to the quintiles of pesticide expenditure. PD HR ratios (HRR) were calculated to compare PD HR across the quintiles of pesticide expenditure. Results Moderate correlation (r=0.518; p<0.001) between PD HR in non-urban micro-regions and pesticide expenditure was observed. In non-urban areas, compared with micro-regions of the first quintile of pesticide use, PD HRR ranged from 1.70 to 5.90 in micro-regions of higher pesticide use. In general, regardless of sex and age, the higher the use of pesticides, the greater the magnitude of PD HRR. Conclusion Our results suggest that pesticide use is associated with PD in Brazil, especially in non-urban areas where pesticides are used more intensively. |
| first_indexed | 2024-04-11T15:37:19Z |
| format | Article |
| id | doaj.art-c218173e3e3f4e9eb589b52b3fb894da |
| institution | Directory Open Access Journal |
| issn | 1414-462X |
| language | English |
| last_indexed | 2024-04-11T15:37:19Z |
| publishDate | 2021-12-01 |
| publisher | Instituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de Janeiro |
| record_format | Article |
| series | Cadernos de Saúde Coletiva |
| spelling | doaj.art-c218173e3e3f4e9eb589b52b3fb894da2022-12-22T04:15:55ZengInstituto de Estudos em Saúde Coletiva da Universidade Federal do Rio de JaneiroCadernos de Saúde Coletiva1414-462X2021-12-0110.1590/1414-462x202129040236Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of BrazilAline de Souza Espindola Santoshttps://orcid.org/0000-0002-5498-3992Noa KrawczykChristine Gibson ParksCarmen Froes Ildes AsmusVolney de Magalhães CâmaraJaime LimaArmando Meyerhttps://orcid.org/0000-0002-5258-8016Abstract Background Few studies have evaluated the role played by pesticide exposure in the development of Parkinson’s disease (PD) in Brazil. Objective This study aimed to investigate the association between pesticide use and PD hospitalization in Brazilian micro-regions. Method Pesticide expenditure per capita in 1985 and PD hospitalization rates (HR) from 1997 to 2007 were calculated for all 552 Brazilian micro-regions. The Spearman's correlation test was used to compare pesticide expenditure and PD HR by sex, age, and urban and non-urban micro-regions. Micro-regions were grouped according to the quintiles of pesticide expenditure. PD HR ratios (HRR) were calculated to compare PD HR across the quintiles of pesticide expenditure. Results Moderate correlation (r=0.518; p<0.001) between PD HR in non-urban micro-regions and pesticide expenditure was observed. In non-urban areas, compared with micro-regions of the first quintile of pesticide use, PD HRR ranged from 1.70 to 5.90 in micro-regions of higher pesticide use. In general, regardless of sex and age, the higher the use of pesticides, the greater the magnitude of PD HRR. Conclusion Our results suggest that pesticide use is associated with PD in Brazil, especially in non-urban areas where pesticides are used more intensively.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1414-462X2021005019204&tlng=ptpesticidesParkinson’s diseaseenvironmental healthhospitalizationsBrazil |
| spellingShingle | Aline de Souza Espindola Santos Noa Krawczyk Christine Gibson Parks Carmen Froes Ildes Asmus Volney de Magalhães Câmara Jaime Lima Armando Meyer Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil Cadernos de Saúde Coletiva pesticides Parkinson’s disease environmental health hospitalizations Brazil |
| title | Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil |
| title_full | Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil |
| title_fullStr | Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil |
| title_full_unstemmed | Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil |
| title_short | Parkinson’s disease hospitalization rates and pesticide use in urban and non-urban regions of Brazil |
| title_sort | parkinson s disease hospitalization rates and pesticide use in urban and non urban regions of brazil |
| topic | pesticides Parkinson’s disease environmental health hospitalizations Brazil |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1414-462X2021005019204&tlng=pt |
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