Computer-aided identification of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) inhibitors from Gymnema sylvestre natural products

Computer-aided identification of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) inhibitors from Gymnema sylvestre natural products

Tuberculosis (TB), an infectious disease caused by multi-drug resistant Mycobacterium tuberculosis (Mtb), has been a global health concern. Mtb affects over a third of the world’s population, causing two million deaths annually due to its dormancy and propensity to spread infection during this perio...

Full description

Bibliographic Details
Main Authors:	Mohibullah Shah, Fatiha Khan, Iqra Ahmad, Cun-Liang Deng, Asia Perveen, Anwar Iqbal, Umar Nishan, Aqal Zaman, Riaz Ullah, Essam A. Ali, Ke Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Pharmacology
Subjects:	multi-drug resistance tuberculosis RpfB dormancy Gymnema sylvestre in-silico
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1325227/full

Similar Items

Antimicrobial activity of Gymnema sylvestre (Asclepiadaceae)
by: Beverly C. David, et al.
Published: (2013-01-01)

Development of quality control parameters for the standardization of gymnema sylvestre
by: Dinesh K. Patel, et al.
Published: (2012-01-01)

Triterpenoids from Gymnema sylvestre and Their Pharmacological Activities
by: Giovanni Di Fabio, et al.
Published: (2014-07-01)

New Pregnane Glycosides from Gymnema sylvestre
by: Rui Xu, et al.
Published: (2015-02-01)

Absence of antidiabetic and hypolipidemic effect of Gymnema sylvestre in non-diabetic and alloxan-diabetic rats
by: Ricardo Galletto, et al.
Published: (2004-08-01)

C-4 Gem-Dimethylated Oleanes of Gymnema sylvestre and Their Pharmacological Activities
by: Giovanni Di Fabio, et al.
Published: (2013-12-01)

Risk assessment of substances used in food supplements: the example of the botanical Gymnema sylvestre
by: German Federal Institute for Risk Assessment (BfR), Germany, et al.
Published: (2018-08-01)

Avaliação da atividade moluscicida da <em>Gymnema sylvestre</em> R. Br., (Asclepiadaceae)
by: Andréa Brustolin, et al.
Published: (2008-05-01)

Acute and sub-acute toxicity profile of crude extract and fractions of Gymnema sylvestre
by: Rofiyat Omolara Raji, et al.
Published: (2021-06-01)

Gymnema sylvestre extract ameliorated streptozotocin‐induced hyperglycemia in T2DM rats via gut microbiota
by: Guilin Chen, et al.
Published: (2023-09-01)

In silico evaluation of naturally isolated triterpene glycosides (TG) from Gymnema sylvestre towards diabetic treatment
by: Rashmi S Shenoy, et al.
Published: (2021-12-01)

The Plant Defense Signal Salicylic Acid Activates the RpfB-Dependent Quorum Sensing Signal Turnover via Altering the Culture and Cytoplasmic pH in the Phytopathogen Xanthomonas campestris
by: Kai Song, et al.
Published: (2022-04-01)

Gymnema sylvestre extract improves PCOS by altering the YAP1 protein in the mouse ovary via mitochondrial changes
by: Aruna Jangam, et al.
Published: (2024-02-01)

Antimicrobial properties and biocompatibility of electrospun poly-ε-caprolactone fibrous mats containing Gymnema sylvestre leaf extract
by: Ramalingam, Raghavendra, et al.
Published: (2021)

Exploring Bioactive Phytochemicals in <i>Gymnema sylvestre</i>: Biomedical Uses and Computational Investigations
by: Uday M. Muddapur, et al.
Published: (2024-02-01)

In vivo immunomodulatory effects of the methanolic leaf extract of Gymnema sylvestre in Swiss albino mice
by: Ahirwal Laxmi, et al.
Published: (2015-01-01)

<i>Gymnema Sylvestre</i> Supplementation Restores Normoglycemia, Corrects Dyslipidemia, and Transcriptionally Modulates Pancreatic and Hepatic Gene Expression in Alloxan-Induced Hyperglycemic Rats
by: Humaira Muzaffar, et al.
Published: (2023-04-01)

Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre
by: Farzana Khan, et al.
Published: (2019-10-01)

Characterization of squalene synthase gene from Gymnema sylvestre R. Br.
by: Kuldeepsingh A. Kalariya, et al.
Published: (2021-01-01)

<b>Efeito da <em>Gymnema sylvestre</em> na elevação da lipidemia após administração de gordura de origem animal em ratos wistar</b> - DOI: 10.4025/actascibiolsci.v26i3.1602
by: Elizete Rosa dos Santos Silva, et al.
Published: (2008-04-01)

<i>Gymnema sylvestre</i> Extract Restores the Autophagic Pathway in Human Glioblastoma Cells U87Mg
by: Rossella Rotondo, et al.
Published: (2021-09-01)

Use of resuscitation promoting factors to screen for tuberculosis infection in household-exposed children in The Gambia
by: W. van Loon, et al.
Published: (2020-07-01)

In vitro antimicrobial potential of extracts and phytoconstituents from Gymnema sylvestre R.Br. leaves and their biosafety evaluation
by: Daljit Singh Arora, et al.
Published: (2017-06-01)

Comparison of anti-inflammatory activities of biogenic gymnema sylvestre- and panicum sumatrense-mediated titanium dioxide nanoparticles
by: Moses Stella Bharathy, et al.
Published: (2021-01-01)

Liquid chromatography-mass spectroscopy and molecular docking analysis of Gymnema sylvestre methanol leaf extract revealed antioxidant potential of quercetin
by: Aminu Ibrahim, et al.
Published: (2021-07-01)

Preformulation studies of Gymnema sylvestre extract powder formulation for hard gelatin capsules
by: F.M. Carbinatto, et al.
Published: (2011-05-01)

Estimation of genetic diversity and population genetic structure in Gymnema sylvestre (Retz.) R. Br. ex Schult. populations using DAMD and ISSR markers
by: Kanchana Vaishnav, et al.
Published: (2023-04-01)

Plant- mediated biosynthesis of Silver nanoparticles from Gymnema sylvestre and their use in phtodegradation of Methyl orange dye
by: Shirish Sadashiv Pingale, et al.
Published: (2018-04-01)

Rapid Screening for α-Glucosidase Inhibitors from Gymnema sylvestre by Affinity Ultrafiltration–HPLC-MS
by: Mingquan Guo, et al.
Published: (2017-04-01)

Characterization of phenylalanine ammonia lyase and revealing flavonoid biosynthesis in Gymnema sylvestre R. Br through transcriptomic approach
by: Kuldeepsingh A. Kalariya, et al.
Published: (2024-03-01)

Five New Pregnane Glycosides from <i>Gymnema sylvestre</i> and Their α-Glucosidase and α-Amylase Inhibitory Activities
by: Phan Van Kiem, et al.
Published: (2020-05-01)

Unlocking the anti‐diabetic potential of Gymnema sylvestre, Trigonella foenum‐graecum, and their combination thereof: An in‐vivo evaluation
by: Muhammad Kashif, et al.
Published: (2023-12-01)

Comparative effectiveness of biorational pesticides for management of Phenacoccus solenopsis Tinsley and Paracoccus marginatus Williams & Granara de Willink in Gymnema sylvestre (Retz.) R.Br. ex Sm
by: Shivakumara Kadanakuppe Thammayya, et al.
Published: (2024-01-01)

Combination of Phyllanthus amarus Schum. & Thonn. and Gymnema sylvestre R. Br. for treatment of diabetes and its long-term complications
by: T. M. Le, et al.
Published: (2021-07-01)

Anti-Tumor Potential of <i>Gymnema sylvestre</i> Saponin Rich Fraction on In Vitro Breast Cancer Cell Lines and In Vivo Tumor-Bearing Mouse Models
by: Abhinav Raj Ghosh, et al.
Published: (2023-01-01)

Molecular docking and prediction of ADME/drug-likeness properties of potentially active antidiabetic compounds isolated from aqueous-methanol extracts of Gymnema sylvestre and Combretum micranthum
by: Chimaobi Ononamadu, et al.
Published: (2021-03-01)

Protective effect of Gymnema sylvestre leaf extract against uranium toxicity in human peripheral blood mononuclear cells
by: Sherin John Joseph, et al.
Published: (2022-04-01)

Eco-Friendly Synthesis of Ni/NiO Nanoparticles Using <i>Gymnema sylvestre</i> Leaves Extract for Antifungal Activity
by: Manish Bhoye, et al.
Published: (2023-03-01)

De novo in vitro shoot morphogenesis from shoot tip-induced callus cultures of Gymnema sylvestre (Retz.) R.Br. ex Sm
by: Tasiu Isah
Published: (2019-01-01)

Gymnema sylvestre as a potential therapeutic agent for PCOS: insights from mRNA differential gene expression and molecular docking analysis
by: Divya Vora, et al.
Published: (2023-08-01)