Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process
The incorporation of graphene with metal oxide has been widely explored in various fields, including energy storage devices, optical applications, biomedical applications, and water remediation. This research aimed to assess the impact of reduced graphene oxide (RGO) doping on the photocatalytic and...
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MDPI AG
2023-06-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/13/5153 |
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| author | ZabnAllah M. Alaizeri Hisham A. Alhadlaq Saad Aldawood Mohd Javed Akhtar Aziz A. Aziz Maqusood Ahamed |
| author_facet | ZabnAllah M. Alaizeri Hisham A. Alhadlaq Saad Aldawood Mohd Javed Akhtar Aziz A. Aziz Maqusood Ahamed |
| author_sort | ZabnAllah M. Alaizeri |
| collection | DOAJ |
| description | The incorporation of graphene with metal oxide has been widely explored in various fields, including energy storage devices, optical applications, biomedical applications, and water remediation. This research aimed to assess the impact of reduced graphene oxide (RGO) doping on the photocatalytic and anticancer properties of In<sub>2</sub>O<sub>3</sub> nanoparticles. Pure and In<sub>2</sub>O<sub>3</sub>/RGO nanocomposites were effectively synthesized using the single-step microwave hydrothermal process. XRD, TEM, SEM, EDX, XPS, Raman, UV–Vis, and PL spectroscopy were carefully utilized to characterize the prepared samples. XRD data showed that synthesized In<sub>2</sub>O<sub>3</sub> nanoparticles had high crystallinity with a decreased crystal size after RGO doping. TEM and SEM images revealed that the In<sub>2</sub>O<sub>3</sub> NPs were spherical and uniformly embedded onto the surface of RGO sheets. Elemental analysis of In<sub>2</sub>O<sub>3</sub>/RGO NC confirmed the presence of In, O, and C without impurities. Raman analysis indicated the successful fabrication of In<sub>2</sub>O<sub>3</sub> onto the RGO surface. Uv–Vis analysis showed that the band gap energy was changed with RGO addition. Raman spectra confirmed that In<sub>2</sub>O<sub>3</sub> nanoparticles were successfully anchored onto the RGO sheet. PL results indicated that the prepared In<sub>2</sub>O<sub>3</sub>/RGO NCs can be applied to enhance photocatalytic activity and biomedical applications. In the degradation experiment, In<sub>2</sub>O<sub>3</sub>/RGO NCs exhibited superior photocatalytic activity compared to that of pure In<sub>2</sub>O<sub>3</sub>. The degradation efficiency of In<sub>2</sub>O<sub>3</sub>/RGO NCs for MB dye was up to 90%. Biological data revealed that the cytotoxicity effect of In<sub>2</sub>O<sub>3</sub>/RGO NCs was higher than In<sub>2</sub>O<sub>3</sub> NPs in human colorectal (HCT116) and liver (HepG2) cancer cells. Importantly, the In<sub>2</sub>O<sub>3</sub>/RGO NCs exhibited better biocompatibility against human normal peripheral blood mononuclear cells (PBMCs). All the results suggest that RGO addition improves the photocatalytic and anticancer activity of In<sub>2</sub>O<sub>3</sub> NPs. This study highlights the potential of In<sub>2</sub>O<sub>3</sub>/RGO NCs as an efficient photocatalyst and therapeutic material for water remediation and biomedicine. |
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| spelling | doaj.art-c219a11ba5154752ab93a50a5c9f7e452023-11-18T17:08:58ZengMDPI AGMolecules1420-30492023-06-012813515310.3390/molecules28135153Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis ProcessZabnAllah M. Alaizeri0Hisham A. Alhadlaq1Saad Aldawood2Mohd Javed Akhtar3Aziz A. Aziz4Maqusood Ahamed5Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi ArabiaThe incorporation of graphene with metal oxide has been widely explored in various fields, including energy storage devices, optical applications, biomedical applications, and water remediation. This research aimed to assess the impact of reduced graphene oxide (RGO) doping on the photocatalytic and anticancer properties of In<sub>2</sub>O<sub>3</sub> nanoparticles. Pure and In<sub>2</sub>O<sub>3</sub>/RGO nanocomposites were effectively synthesized using the single-step microwave hydrothermal process. XRD, TEM, SEM, EDX, XPS, Raman, UV–Vis, and PL spectroscopy were carefully utilized to characterize the prepared samples. XRD data showed that synthesized In<sub>2</sub>O<sub>3</sub> nanoparticles had high crystallinity with a decreased crystal size after RGO doping. TEM and SEM images revealed that the In<sub>2</sub>O<sub>3</sub> NPs were spherical and uniformly embedded onto the surface of RGO sheets. Elemental analysis of In<sub>2</sub>O<sub>3</sub>/RGO NC confirmed the presence of In, O, and C without impurities. Raman analysis indicated the successful fabrication of In<sub>2</sub>O<sub>3</sub> onto the RGO surface. Uv–Vis analysis showed that the band gap energy was changed with RGO addition. Raman spectra confirmed that In<sub>2</sub>O<sub>3</sub> nanoparticles were successfully anchored onto the RGO sheet. PL results indicated that the prepared In<sub>2</sub>O<sub>3</sub>/RGO NCs can be applied to enhance photocatalytic activity and biomedical applications. In the degradation experiment, In<sub>2</sub>O<sub>3</sub>/RGO NCs exhibited superior photocatalytic activity compared to that of pure In<sub>2</sub>O<sub>3</sub>. The degradation efficiency of In<sub>2</sub>O<sub>3</sub>/RGO NCs for MB dye was up to 90%. Biological data revealed that the cytotoxicity effect of In<sub>2</sub>O<sub>3</sub>/RGO NCs was higher than In<sub>2</sub>O<sub>3</sub> NPs in human colorectal (HCT116) and liver (HepG2) cancer cells. Importantly, the In<sub>2</sub>O<sub>3</sub>/RGO NCs exhibited better biocompatibility against human normal peripheral blood mononuclear cells (PBMCs). All the results suggest that RGO addition improves the photocatalytic and anticancer activity of In<sub>2</sub>O<sub>3</sub> NPs. This study highlights the potential of In<sub>2</sub>O<sub>3</sub>/RGO NCs as an efficient photocatalyst and therapeutic material for water remediation and biomedicine.https://www.mdpi.com/1420-3049/28/13/5153In<sub>2</sub>O<sub>3</sub>/RGOmicrowave hydrothermal methoddegradationcytotoxicity effectbiocompatibility |
| spellingShingle | ZabnAllah M. Alaizeri Hisham A. Alhadlaq Saad Aldawood Mohd Javed Akhtar Aziz A. Aziz Maqusood Ahamed Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process Molecules In<sub>2</sub>O<sub>3</sub>/RGO microwave hydrothermal method degradation cytotoxicity effect biocompatibility |
| title | Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process |
| title_full | Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process |
| title_fullStr | Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process |
| title_full_unstemmed | Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process |
| title_short | Photocatalytic Degradation of Methylene Blue and Anticancer Response of In<sub>2</sub>O<sub>3</sub>/RGO Nanocomposites Prepared by a Microwave-Assisted Hydrothermal Synthesis Process |
| title_sort | photocatalytic degradation of methylene blue and anticancer response of in sub 2 sub o sub 3 sub rgo nanocomposites prepared by a microwave assisted hydrothermal synthesis process |
| topic | In<sub>2</sub>O<sub>3</sub>/RGO microwave hydrothermal method degradation cytotoxicity effect biocompatibility |
| url | https://www.mdpi.com/1420-3049/28/13/5153 |
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