Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium

Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium

Mycobacterium avium (Mav) complex is increasingly reported to cause non-tuberculous infections in individuals with a compromised immune system. Treatment is complicated and no vaccines are available. Previous studies have shown some potential of using genetically modified Mycobacterium smegmatis (Ms...

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Bibliographic Details
Main Authors: Nisha Kannan, Markus Haug, Magnus Steigedal, Trude Helen Flo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium avium
Mycobacterium smegmatis
ESX-3
infection
vaccine
CD8+ Tc17
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01116/full

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