General Purpose Pharmacokinetic-Pharmacodynamic Models for Target-Controlled Infusion of Anaesthetic Drugs: A Narrative Review

General Purpose Pharmacokinetic-Pharmacodynamic Models for Target-Controlled Infusion of Anaesthetic Drugs: A Narrative Review

Target controlled infusion (TCI) is a clinically-available and widely-used computer-controlled method of drug administration, adjusting the drug titration towards user selected plasma- or effect-site concentrations, calculated according to pharmacokinetic-pharmacodynamic (PKPD) models. Although this...

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Bibliographic Details
Main Authors: Ophélie Vandemoortele, Laura N. Hannivoort, Florian Vanhoorebeeck, Michel M. R. F. Struys, Hugo E. M. Vereecke
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Clinical Medicine
Subjects:
propofol
remifentanil
dexmedetomidine
general purpose pharmacokinetic-pharmacodynamic models
target controlled infusion
Online Access:https://www.mdpi.com/2077-0383/11/9/2487

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