Deficient beta-mannosylation of Candida albicans phospholipomannan affects the proinflammatory response in macrophages.

Deficient beta-mannosylation of Candida albicans phospholipomannan affects the proinflammatory response in macrophages.

Candida albicans produces a complex glycosphingolipid called phospholipomannan (PLM), which is present on the cell-wall surface of yeast and shed upon contact with host cells. The glycan moiety of PLM is composed of β-mannosides with degrees of polymerization up to 19 in C. albicans serotype A. PLM...

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Bibliographic Details
Main Authors: Audrey Devillers, Flavie Courjol, Chantal Fradin, Agnes Coste, Daniel Poulain, Bernard Pipy, Emerson Soares Bernardes, Thierry Jouault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868656?pdf=render

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