Conformationally Altered C-Reactive Protein Capable of Binding to Atherogenic Lipoproteins Reduces Atherosclerosis

Conformationally Altered C-Reactive Protein Capable of Binding to Atherogenic Lipoproteins Reduces Atherosclerosis

The aim of this study was to test the hypothesis that C-reactive protein (CRP) protects against the development of atherosclerosis and that a conformational alteration of wild-type CRP is necessary for CRP to do so. Atherosclerosis is an inflammatory cardiovascular disease and CRP is a plasma protei...

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Bibliographic Details
Main Authors: Asmita Pathak, Sanjay K. Singh, Douglas P. Thewke, Alok Agrawal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
atherosclerosis
C-reactive protein
inflammation
low-density lipoprotein
phosphocholine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01780/full

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