Expression pattern and clinical significance of β-catenin gene and protein in patients with primary malignant and benign bone tumors

Abstract This study is aimed to unravel the status of local and circulating β-catenin in different primary bone tumors and its relevance to tumor types, severity, and chemotherapy. The β-catenin mRNA expression level and the expression of the protein (intensity level) were evaluated in tumor tissue...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Narges Khademian, Alireza Mirzaei, Ameinh Hosseini, Leila Zare, Shima Nazem, Pegah Babaheidarian, Alireza Sheikhi, Zohreh Abdolvahabi, Mostafa Ibrahimi, Khodamorad Jamshidi, Mahtab Rahbar, Vahid Salimi, Masoumeh Tavakoli-Yaraki
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2022-06-01
Schriftenreihe:Scientific Reports
Online Zugang:https://doi.org/10.1038/s41598-022-13685-1