Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells
The development of acute pancreatitis (AP) is associated with intracellular events in pancreatic cells, as well as with early and late inflammatory responses; however, their underlying mechanisms remain unclear. This study investigated trypsinogen activation peptide (TAP)-induced release of high mob...
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| Format: | Article |
| Language: | English |
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De Gruyter
2017-09-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | http://www.degruyter.com/view/j/med.2017.12.issue-1/med-2017-0043/med-2017-0043.xml?format=INT |
| _version_ | 1830132228617666560 |
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| author | Wang Guoliang Liu Yan Dui Danhua Bai Liang Liu Yao Tian Fei Wei Wei |
| author_facet | Wang Guoliang Liu Yan Dui Danhua Bai Liang Liu Yao Tian Fei Wei Wei |
| author_sort | Wang Guoliang |
| collection | DOAJ |
| description | The development of acute pancreatitis (AP) is associated with intracellular events in pancreatic cells, as well as with early and late inflammatory responses; however, their underlying mechanisms remain unclear. This study investigated trypsinogen activation peptide (TAP)-induced release of high mobility group box-l (HMGB1) from pancreatic acinar cells and how ethyl pyruvate (EP) affects this release. |
| first_indexed | 2024-12-17T06:30:37Z |
| format | Article |
| id | doaj.art-c21d98444e2944a0b2225f28ed1e116a |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-12-17T06:30:37Z |
| publishDate | 2017-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-c21d98444e2944a0b2225f28ed1e116a2022-12-21T22:00:09ZengDe GruyterOpen Medicine2391-54632017-09-0112129329810.1515/med-2017-0043med-2017-0043Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cellsWang Guoliang0Liu Yan1Dui Danhua2Bai Liang3Liu Yao4Tian Fei5Wei Wei6Department of Hepatobiliaropancreatic Surgery, Guizhou Provincial People’s Hospital, Guiyang, 550002, ChinaDepartment of Hepatobiliaropancreatic Surgery, Guizhou Provincial People’s Hospital, Guiyang, 550002, ChinaDepartment of Hepatopancreatobiliary Surgery, Affiliated Hospital of Zunyi Medical, College, Zunyi563003, ChinaChina Department of Hepatobiliaropancreatic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi563003, ChinaChina Department of Hepatobiliaropancreatic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi563003, ChinaChina Department of Hepatobiliaropancreatic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi563003, ChinaChina Department of Hepatobiliaropancreatic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi563003, ChinaThe development of acute pancreatitis (AP) is associated with intracellular events in pancreatic cells, as well as with early and late inflammatory responses; however, their underlying mechanisms remain unclear. This study investigated trypsinogen activation peptide (TAP)-induced release of high mobility group box-l (HMGB1) from pancreatic acinar cells and how ethyl pyruvate (EP) affects this release.http://www.degruyter.com/view/j/med.2017.12.issue-1/med-2017-0043/med-2017-0043.xml?format=INTPancreatic acinar cellTrypsinogen activation peptideHigh mobility group box-1Ethyl pyruvateRat |
| spellingShingle | Wang Guoliang Liu Yan Dui Danhua Bai Liang Liu Yao Tian Fei Wei Wei Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells Open Medicine Pancreatic acinar cell Trypsinogen activation peptide High mobility group box-1 Ethyl pyruvate Rat |
| title | Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells |
| title_full | Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells |
| title_fullStr | Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells |
| title_full_unstemmed | Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells |
| title_short | Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells |
| title_sort | trypsinogen activation peptide induces hmgb1 release from rat pancreatic acinar cells |
| topic | Pancreatic acinar cell Trypsinogen activation peptide High mobility group box-1 Ethyl pyruvate Rat |
| url | http://www.degruyter.com/view/j/med.2017.12.issue-1/med-2017-0043/med-2017-0043.xml?format=INT |
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