Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study
Objective: Even though antibiotic resistance is one of the most serious threats to global public health, it is becoming more common due to inappropriate antibiotic prescribing patterns. Thus, the purpose of this study is to assess antibiotic prescribing patterns among inpatients at an Ethiopian comp...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-05-01
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| Series: | SAGE Open Medicine |
| Online Access: | https://doi.org/10.1177/20503121221096608 |
| _version_ | 1811233677925941248 |
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| author | Tesfaye Yimer Tadesse Mulugeta Molla Yohannis Shumet Yimer Benyas Shishigie Tarekegn Belayneh Kefale |
| author_facet | Tesfaye Yimer Tadesse Mulugeta Molla Yohannis Shumet Yimer Benyas Shishigie Tarekegn Belayneh Kefale |
| author_sort | Tesfaye Yimer Tadesse |
| collection | DOAJ |
| description | Objective: Even though antibiotic resistance is one of the most serious threats to global public health, it is becoming more common due to inappropriate antibiotic prescribing patterns. Thus, the purpose of this study is to assess antibiotic prescribing patterns among inpatients at an Ethiopian comprehensive specialized hospital. Methods: An institutional-based cross-sectional study was used. During the study period, data were collected from the charts of admitted patients in selected wards of Debre Tabor comprehensive specialized hospital. The World Health Organization’s developed questionnaire and conventional antibiotic prescribing indicators were used to assess rational drug usage, with an emphasis on antibiotic prescribing trends. The data were analyzed using SPSS 25.0 statistical software. Results: For 861 patients admitted to medical and pediatric wards, a total of 1444 antibiotics were prescribed. Overall, 60.6% of inpatients were prescribed at least one antibiotic, with an average (mean ± SD) number of antibiotics prescribed per patient of 1.7 ± 1.6. During their hospital stay, patients were given antibiotics for an average (mean ± SD) of 6.4 ± 2.7 days. Furthermore, 83.3% of antibiotics were prescribed for therapeutic purposes, whereas 100% were provided for empiric purposes. Ceftriaxone was the most commonly administered antibiotic in the study settings (49.2%). During the study period, Debre Tabor comprehensive specialized hospital had access to 67.5% of key antibiotics. Conclusion: The antibiotic prescribing pattern in our study diverged from the World Health Organization-recommended guidelines. Furthermore, all antibiotics were given without a culture or sensitivity test in every case. Setting up an antibiotic stewardship program, introducing antibiotic use based on culture and sensitivity tests, and adopting institutional guidelines could all help to address this issue. |
| first_indexed | 2024-04-12T11:24:39Z |
| format | Article |
| id | doaj.art-c2247f526c774d09a94dfb66a9cabb1a |
| institution | Directory Open Access Journal |
| issn | 2050-3121 |
| language | English |
| last_indexed | 2024-04-12T11:24:39Z |
| publishDate | 2022-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medicine |
| spelling | doaj.art-c2247f526c774d09a94dfb66a9cabb1a2022-12-22T03:35:16ZengSAGE PublishingSAGE Open Medicine2050-31212022-05-011010.1177/20503121221096608Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional studyTesfaye Yimer Tadesse0Mulugeta Molla1Yohannis Shumet Yimer2Benyas Shishigie Tarekegn3Belayneh Kefale4Pharmacology and Toxicology Unit, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaPharmacology and Toxicology Unit, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaPharmaceutics and Social Pharmacy Unit, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, EthiopiaClinical Pharmacy Unit, Debre Tabor Comprehensive Specialized Hospital, Debre Tabor, EthiopiaClinical Pharmacy Unit, Department of Pharmacy, College of Medical and Health Sciences, Bahir Dar University, Bahir Dar, EthiopiaObjective: Even though antibiotic resistance is one of the most serious threats to global public health, it is becoming more common due to inappropriate antibiotic prescribing patterns. Thus, the purpose of this study is to assess antibiotic prescribing patterns among inpatients at an Ethiopian comprehensive specialized hospital. Methods: An institutional-based cross-sectional study was used. During the study period, data were collected from the charts of admitted patients in selected wards of Debre Tabor comprehensive specialized hospital. The World Health Organization’s developed questionnaire and conventional antibiotic prescribing indicators were used to assess rational drug usage, with an emphasis on antibiotic prescribing trends. The data were analyzed using SPSS 25.0 statistical software. Results: For 861 patients admitted to medical and pediatric wards, a total of 1444 antibiotics were prescribed. Overall, 60.6% of inpatients were prescribed at least one antibiotic, with an average (mean ± SD) number of antibiotics prescribed per patient of 1.7 ± 1.6. During their hospital stay, patients were given antibiotics for an average (mean ± SD) of 6.4 ± 2.7 days. Furthermore, 83.3% of antibiotics were prescribed for therapeutic purposes, whereas 100% were provided for empiric purposes. Ceftriaxone was the most commonly administered antibiotic in the study settings (49.2%). During the study period, Debre Tabor comprehensive specialized hospital had access to 67.5% of key antibiotics. Conclusion: The antibiotic prescribing pattern in our study diverged from the World Health Organization-recommended guidelines. Furthermore, all antibiotics were given without a culture or sensitivity test in every case. Setting up an antibiotic stewardship program, introducing antibiotic use based on culture and sensitivity tests, and adopting institutional guidelines could all help to address this issue.https://doi.org/10.1177/20503121221096608 |
| spellingShingle | Tesfaye Yimer Tadesse Mulugeta Molla Yohannis Shumet Yimer Benyas Shishigie Tarekegn Belayneh Kefale Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study SAGE Open Medicine |
| title | Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study |
| title_full | Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study |
| title_fullStr | Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study |
| title_full_unstemmed | Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study |
| title_short | Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study |
| title_sort | evaluation of antibiotic prescribing patterns among inpatients using world health organization indicators a cross sectional study |
| url | https://doi.org/10.1177/20503121221096608 |
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