Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol

Abstract Background Recent increasing trends in breast cancer incidence and survival have resulted in unprecedented numbers of cancer survivors in the general population. A cancer diagnosis may have a profound psychological impact, and breast cancer treatments often cause long-term physical sequelae...

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Main Authors: Helena Carreira, Rachael Williams, Martin Müller, Rhea Harewood, Krishnan Bhaskaran
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Systematic Reviews
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13643-017-0551-2
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author Helena Carreira
Rachael Williams
Martin Müller
Rhea Harewood
Krishnan Bhaskaran
author_facet Helena Carreira
Rachael Williams
Martin Müller
Rhea Harewood
Krishnan Bhaskaran
author_sort Helena Carreira
collection DOAJ
description Abstract Background Recent increasing trends in breast cancer incidence and survival have resulted in unprecedented numbers of cancer survivors in the general population. A cancer diagnosis may have a profound psychological impact, and breast cancer treatments often cause long-term physical sequelae, potentially affecting women’s mental health. The aim of this systematic review is to identify and summarise all studies that have compared mental health outcomes in breast cancer survivors, versus women who did not have cancer. Methods This study will be a systematic review of the literature. Four databases, including MEDLINE and PsycINFO, will be searched to identify potentially relevant studies. The search expressions will use a Boolean logic, including terms for the target population (women who have had breast cancer), outcomes (psychiatric disorders) and comparators (e.g. risk, hazard). All mental disorders will be eligible, except those with onset normally occurring during childhood or strong genetic basis (e.g. Huntington disease). The eligibility of the studies will be assessed in two phases: (1) considering the information provided in the title and abstract; (2) evaluating the full text. Studies including women diagnosed with breast cancer 1 year or more ago and that provide original data on mental health outcomes will be eligible. Studies in which all women were undergoing surgery, chemotherapy or radiotherapy, or hospitalised or institutionalised, will be excluded, as well as studies that include patients selected on the basis of symptomatology. Two investigators will do the screening of the references and the data extraction independently, with results compared and discrepancies resolved by involving a third investigator when necessary. Study quality and risk of bias will be assessed across six broad domains. Results will be summarised by outcome, and summary measures of frequency and/or association will be computed if possible. Discussion This review will summarise the evidence on the mental health outcomes of women who have been diagnosed with breast cancer. This information can be used to motivate further research and increase understanding of the most common mental health conditions affecting this growing population of women. Systematic review registration PROSPERO CRD42017056946
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spelling doaj.art-c227c9da5fcc4c13978d3c6bf12ebb552022-12-22T01:51:18ZengBMCSystematic Reviews2046-40532017-08-01611610.1186/s13643-017-0551-2Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocolHelena Carreira0Rachael Williams1Martin Müller2Rhea Harewood3Krishnan Bhaskaran4Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical MedicineClinical Practice Research Datalink (CPRD), Medicines and Healthcare products Regulatory AgencyDepartment of Emergency Medicine, Inselspital, Bern University Hospital, University of BernDepartment of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical MedicineDepartment of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical MedicineAbstract Background Recent increasing trends in breast cancer incidence and survival have resulted in unprecedented numbers of cancer survivors in the general population. A cancer diagnosis may have a profound psychological impact, and breast cancer treatments often cause long-term physical sequelae, potentially affecting women’s mental health. The aim of this systematic review is to identify and summarise all studies that have compared mental health outcomes in breast cancer survivors, versus women who did not have cancer. Methods This study will be a systematic review of the literature. Four databases, including MEDLINE and PsycINFO, will be searched to identify potentially relevant studies. The search expressions will use a Boolean logic, including terms for the target population (women who have had breast cancer), outcomes (psychiatric disorders) and comparators (e.g. risk, hazard). All mental disorders will be eligible, except those with onset normally occurring during childhood or strong genetic basis (e.g. Huntington disease). The eligibility of the studies will be assessed in two phases: (1) considering the information provided in the title and abstract; (2) evaluating the full text. Studies including women diagnosed with breast cancer 1 year or more ago and that provide original data on mental health outcomes will be eligible. Studies in which all women were undergoing surgery, chemotherapy or radiotherapy, or hospitalised or institutionalised, will be excluded, as well as studies that include patients selected on the basis of symptomatology. Two investigators will do the screening of the references and the data extraction independently, with results compared and discrepancies resolved by involving a third investigator when necessary. Study quality and risk of bias will be assessed across six broad domains. Results will be summarised by outcome, and summary measures of frequency and/or association will be computed if possible. Discussion This review will summarise the evidence on the mental health outcomes of women who have been diagnosed with breast cancer. This information can be used to motivate further research and increase understanding of the most common mental health conditions affecting this growing population of women. Systematic review registration PROSPERO CRD42017056946http://link.springer.com/article/10.1186/s13643-017-0551-2Breast neoplasmsSurvivorsMental healthMental disordersSystematic reviewProtocol
spellingShingle Helena Carreira
Rachael Williams
Martin Müller
Rhea Harewood
Krishnan Bhaskaran
Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
Systematic Reviews
Breast neoplasms
Survivors
Mental health
Mental disorders
Systematic review
Protocol
title Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
title_full Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
title_fullStr Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
title_full_unstemmed Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
title_short Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol
title_sort adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer systematic review protocol
topic Breast neoplasms
Survivors
Mental health
Mental disorders
Systematic review
Protocol
url http://link.springer.com/article/10.1186/s13643-017-0551-2
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