Lemierre's syndrome: A rare cause of multifocal infection in an adolescent

Lemierre's syndrome is a rare disease characterized by septic thrombophlebitis of the internal jugular vein with septic emboli causing multifocal infection. This syndrome is most commonly seen after an upper respiratory tract infection in the adolescent population. We present a case of a teenag...

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Main Authors: Ruchi Amin, Thomas Fretz, Carroll Harmon, Kaveh Vali
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Pediatric Surgery Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213576622001774
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author Ruchi Amin
Thomas Fretz
Carroll Harmon
Kaveh Vali
author_facet Ruchi Amin
Thomas Fretz
Carroll Harmon
Kaveh Vali
author_sort Ruchi Amin
collection DOAJ
description Lemierre's syndrome is a rare disease characterized by septic thrombophlebitis of the internal jugular vein with septic emboli causing multifocal infection. This syndrome is most commonly seen after an upper respiratory tract infection in the adolescent population. We present a case of a teenage patient diagnosed with Epstein-Barr Virus (EBV) who presented to our tertiary care facility in multisystem organ failure with initial findings concerning for necrotizing fasciitis of the retroperitoneum. The patient underwent surgical debridement with frank purulence in the retroperitoneal space and emphysematous osteomyelitis of the right ilium. F. necrophorum was isolated from surgical specimens which led to the suspicion of Lemierre's syndrome. Further work up revealed internal jugular vein thrombosis, as well as multifocal inoculation with infection in the ankle, hip, chest, and neck confirming the clinical diagnosis. Lemierre's syndrome is associated with significant morbidity and can be fatal if not promptly recognized and treated. Therefore, early identification is essential to providing appropriate medical and surgical care.
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spelling doaj.art-c22b9c98fef44432ac9b19bd1b3d94892022-12-22T04:01:45ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662022-09-0184102350Lemierre's syndrome: A rare cause of multifocal infection in an adolescentRuchi Amin0Thomas Fretz1Carroll Harmon2Kaveh Vali3Corresponding author. 1001 Main Street Ste #3, Buffalo, NY, 14203, USA.; Division of Pediatric Surgery, Department of Surgery, John R. Oishei Children's Hospital, University at Buffalo, Buffalo, NY, USADivision of Pediatric Surgery, Department of Surgery, John R. Oishei Children's Hospital, University at Buffalo, Buffalo, NY, USADivision of Pediatric Surgery, Department of Surgery, John R. Oishei Children's Hospital, University at Buffalo, Buffalo, NY, USADivision of Pediatric Surgery, Department of Surgery, John R. Oishei Children's Hospital, University at Buffalo, Buffalo, NY, USALemierre's syndrome is a rare disease characterized by septic thrombophlebitis of the internal jugular vein with septic emboli causing multifocal infection. This syndrome is most commonly seen after an upper respiratory tract infection in the adolescent population. We present a case of a teenage patient diagnosed with Epstein-Barr Virus (EBV) who presented to our tertiary care facility in multisystem organ failure with initial findings concerning for necrotizing fasciitis of the retroperitoneum. The patient underwent surgical debridement with frank purulence in the retroperitoneal space and emphysematous osteomyelitis of the right ilium. F. necrophorum was isolated from surgical specimens which led to the suspicion of Lemierre's syndrome. Further work up revealed internal jugular vein thrombosis, as well as multifocal inoculation with infection in the ankle, hip, chest, and neck confirming the clinical diagnosis. Lemierre's syndrome is associated with significant morbidity and can be fatal if not promptly recognized and treated. Therefore, early identification is essential to providing appropriate medical and surgical care.http://www.sciencedirect.com/science/article/pii/S2213576622001774Lemierre's syndromeOsteomyelitisThrombophlebitis
spellingShingle Ruchi Amin
Thomas Fretz
Carroll Harmon
Kaveh Vali
Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
Journal of Pediatric Surgery Case Reports
Lemierre's syndrome
Osteomyelitis
Thrombophlebitis
title Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
title_full Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
title_fullStr Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
title_full_unstemmed Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
title_short Lemierre's syndrome: A rare cause of multifocal infection in an adolescent
title_sort lemierre s syndrome a rare cause of multifocal infection in an adolescent
topic Lemierre's syndrome
Osteomyelitis
Thrombophlebitis
url http://www.sciencedirect.com/science/article/pii/S2213576622001774
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AT kavehvali lemierressyndromeararecauseofmultifocalinfectioninanadolescent