Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin
The GnRH agonist buserelin (GnRH), used to synchronize ovulation in weaned sows, attains only 70–80% effectivity, owing to several reasons of ovarian origin. This study evaluated in particular whether mean ovarian follicle size at treatment and the season of weaning are among those influencing GnRH...
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2020-10-01
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| author | Tania P. Lopes Lorena Padilla Alfonso Bolarin Heriberto Rodriguez-Martinez Jordi Roca |
| author_facet | Tania P. Lopes Lorena Padilla Alfonso Bolarin Heriberto Rodriguez-Martinez Jordi Roca |
| author_sort | Tania P. Lopes |
| collection | DOAJ |
| description | The GnRH agonist buserelin (GnRH), used to synchronize ovulation in weaned sows, attains only 70–80% effectivity, owing to several reasons of ovarian origin. This study evaluated in particular whether mean ovarian follicle size at treatment and the season of weaning are among those influencing GnRH responsiveness. The experiment was carried out in a temperate-region farm with 352 sows of 1–6 parities weaned either in winter–spring (WS, 174 sows) or in summer–autumn (SA, 178 sows). The sows were randomized into two groups: GnRH (10 µg of buserelin acetate at 86 h after weaning, 172 sows) and control (180 sows). The ovaries were transrectally scanned from weaning to ovulation and the sows clustered according to their mean follicular size at treatment time: small (<0.5 cm in diameter), medium (0.5 to 0.64 cm) and large (0.65 to 1.09 cm). In total, 88.33% of the GnRH-treated sows ovulated, with 82% of them within the expected time window (120–132 h after weaning). In contrast, 95.45% of the unresponsive sows had small follicles at the time of treatment and were mostly weaned in SA (20.45%) than in WS (4.76%). In conclusion, the conspicuous presence of sows having small ovarian follicles at treatment time compromises the efficiency of the GnRH agonist buserelin to synchronize ovulation in weaned sows, which occurs more frequently in summer–autumn weaning. |
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| issn | 2076-2615 |
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| spelling | doaj.art-c22e94e4a72a441693d8d437eff8ba3f2023-11-20T18:54:11ZengMDPI AGAnimals2076-26152020-10-011011197910.3390/ani10111979Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist BuserelinTania P. Lopes0Lorena Padilla1Alfonso Bolarin2Heriberto Rodriguez-Martinez3Jordi Roca4Department of Medicine and Animal Surgery, Veterinary Science, University of Murcia, 30100 Murcia, SpainDepartment of Medicine and Animal Surgery, Veterinary Science, University of Murcia, 30100 Murcia, SpainAIM Iberica, Topigs Norsvin España, 20290 Madrid, SpainDepartment of Biomedical and Clinical Sciences (BKV), Linköping University, SE-58185 Linköping, SwedenDepartment of Medicine and Animal Surgery, Veterinary Science, University of Murcia, 30100 Murcia, SpainThe GnRH agonist buserelin (GnRH), used to synchronize ovulation in weaned sows, attains only 70–80% effectivity, owing to several reasons of ovarian origin. This study evaluated in particular whether mean ovarian follicle size at treatment and the season of weaning are among those influencing GnRH responsiveness. The experiment was carried out in a temperate-region farm with 352 sows of 1–6 parities weaned either in winter–spring (WS, 174 sows) or in summer–autumn (SA, 178 sows). The sows were randomized into two groups: GnRH (10 µg of buserelin acetate at 86 h after weaning, 172 sows) and control (180 sows). The ovaries were transrectally scanned from weaning to ovulation and the sows clustered according to their mean follicular size at treatment time: small (<0.5 cm in diameter), medium (0.5 to 0.64 cm) and large (0.65 to 1.09 cm). In total, 88.33% of the GnRH-treated sows ovulated, with 82% of them within the expected time window (120–132 h after weaning). In contrast, 95.45% of the unresponsive sows had small follicles at the time of treatment and were mostly weaned in SA (20.45%) than in WS (4.76%). In conclusion, the conspicuous presence of sows having small ovarian follicles at treatment time compromises the efficiency of the GnRH agonist buserelin to synchronize ovulation in weaned sows, which occurs more frequently in summer–autumn weaning.https://www.mdpi.com/2076-2615/10/11/1979weaned sowsovarian folliclesovulation synchronizationbuserelin |
| spellingShingle | Tania P. Lopes Lorena Padilla Alfonso Bolarin Heriberto Rodriguez-Martinez Jordi Roca Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin Animals weaned sows ovarian follicles ovulation synchronization buserelin |
| title | Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin |
| title_full | Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin |
| title_fullStr | Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin |
| title_full_unstemmed | Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin |
| title_short | Weaned Sows with Small Ovarian Follicles Respond Poorly to the GnRH Agonist Buserelin |
| title_sort | weaned sows with small ovarian follicles respond poorly to the gnrh agonist buserelin |
| topic | weaned sows ovarian follicles ovulation synchronization buserelin |
| url | https://www.mdpi.com/2076-2615/10/11/1979 |
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