Administration of allogeneic mesenchymal stem cells in lengthening phase accelerates early bone consolidation in rat distraction osteogenesis model

Administration of allogeneic mesenchymal stem cells in lengthening phase accelerates early bone consolidation in rat distraction osteogenesis model

Abstract Background Distraction osteogenesis (DO) is a surgical technique to promote bone regeneration which may require long duration for bone consolidation. Bone marrow-derived mesenchymal stem cells (MSCs) have been applied to accelerate bone formation in DO. However, the optimal time point for c...

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Bibliographic Details
Main Authors: Yanhua Yang, Qi Pan, Kaijie Zou, Haixing Wang, Xiaoting Zhang, Zhengmeng Yang, Wayne Yuk Wai Lee, Bo Wei, Weidong Gu, Yunzhi Peter Yang, Sien Lin, Gang Li
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Distraction osteogenesis
Mesenchymal stem cells
Bone consolidation
Cytokines
Online Access:http://link.springer.com/article/10.1186/s13287-020-01635-5

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