Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

There are currently around 200 SARS-CoV-2 candidate vaccines in preclinical and clinical trials throughout the world. The various candidates employ a range of vaccine strategies including some novel approaches. Currently, the goal is to prove that they are safe and immunogenic in humans (phase 1/2 s...

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Bibliographic Details
Main Authors:	Katie L. Flanagan, Emma Best, Nigel W. Crawford, Michelle Giles, Archana Koirala, Kristine Macartney, Fiona Russell, Benjamin W. Teh, Sophie CH Wen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Series:	Frontiers in Immunology
Subjects:	antibody dependent enhancement (ADE) adverse events of special interest (AESI) bacillus Calmette-Guérin (BCG) cell mediated immunity Coalition for Epidemic Preparedness Innovations (CEPI) innate immunity
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2020.579250/full

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