Transcriptomic analysis of glutamate-induced HT22 neurotoxicity as a model for screening anti-Alzheimer’s drugs

Abstract Glutamate-induced neurotoxicity in the HT22 mouse hippocampal neuronal cell line has been recognized as a valuable cell model for the study of neurotoxicity associated with neurodegenerative diseases including Alzheimer’s disease (AD). However, the relevance of this cell model for AD pathog...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Anchalee Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W. Hu, Tewarit Sarachana, Tewin Tencomnao
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2023-05-01
Schriftenreihe:Scientific Reports
Online Zugang:https://doi.org/10.1038/s41598-023-34183-y