Initiation of combined antiretroviral therapy confers suboptimal beneficial effects on neurovascular function in people with HIV

Initiation of combined antiretroviral therapy confers suboptimal beneficial effects on neurovascular function in people with HIV

IntroductionDue to advances in combined anti-retroviral treatment (cART), there is an increased burden of age-related cerebrovascular disease (CBVD), in people living with HIV (PWH). The underlying CNS injury can be assessed by measuring cerebral blood flow (CBF) and cerebrovascular reactivity (CVR)...

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Bibliographic Details
Main Authors: Meera V. Singh, Md Nasir Uddin, Vir B. Singh, Angelique N. Peterson, Kyle D. Murray, Yuchuan Zhuang, Alicia Tyrell, Lu Wang, Madalina E. Tivarus, Jianhui Zhong, Xing Qiu, Giovanni Schifitto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Neurology
Subjects:
HIV
cART
neuroinflammation
neuroimaging
cerebral vascular reactivity
cerebral blood flow
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1240300/full

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