High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating
Guided-mode resonance (GMR) sensors are widely used as biosensors with the advantages of simple structure, easy detection schemes, high efficiency, and narrow linewidth. However, their applications are limited by their relatively low sensitivity (<200 nm/RIU) and in turn low figure of merit (FOM,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/11/7/221 |
| _version_ | 1797527555622830080 |
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| author | Chengrui Zhang Yi Zhou Lan Mi Jiong Ma Xiang Wu Yiyan Fei |
| author_facet | Chengrui Zhang Yi Zhou Lan Mi Jiong Ma Xiang Wu Yiyan Fei |
| author_sort | Chengrui Zhang |
| collection | DOAJ |
| description | Guided-mode resonance (GMR) sensors are widely used as biosensors with the advantages of simple structure, easy detection schemes, high efficiency, and narrow linewidth. However, their applications are limited by their relatively low sensitivity (<200 nm/RIU) and in turn low figure of merit (FOM, <100 1/RIU). Many efforts have been made to enhance the sensitivity or FOM, separately. To enhance the sensitivity and FOM simultaneously for more sensitive sensing, we proposed a metal layer-assisted double-grating (MADG) structure with the evanescent field extending to the sensing region enabled by the metal reflector layer underneath the double-grating. The influence of structural parameters was systematically investigated. Bulk sensitivity of 550.0 nm/RIU and FOM of 1571.4 1/RIU were obtained after numerical optimization. Compared with a single-grating structure, the surface sensitivity of the double-grating structure for protein adsorption increases by a factor of 2.4 times. The as-proposed MADG has a great potential to be a biosensor with high sensitivity and high accuracy. |
| first_indexed | 2024-03-10T09:45:22Z |
| format | Article |
| id | doaj.art-c240e92187d946a7a76b6c07c217d9ed |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T09:45:22Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-c240e92187d946a7a76b6c07c217d9ed2023-11-22T03:19:46ZengMDPI AGBiosensors2079-63742021-07-0111722110.3390/bios11070221High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-GratingChengrui Zhang0Yi Zhou1Lan Mi2Jiong Ma3Xiang Wu4Yiyan Fei5Department of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaDepartment of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaDepartment of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaDepartment of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaDepartment of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaDepartment of Optical Science and Engineering, Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Key Laboratory of Micro and Nano Photonic Structures (Ministry of Education), School of Information Science and Technology, Fudan University, Shanghai 200433, ChinaGuided-mode resonance (GMR) sensors are widely used as biosensors with the advantages of simple structure, easy detection schemes, high efficiency, and narrow linewidth. However, their applications are limited by their relatively low sensitivity (<200 nm/RIU) and in turn low figure of merit (FOM, <100 1/RIU). Many efforts have been made to enhance the sensitivity or FOM, separately. To enhance the sensitivity and FOM simultaneously for more sensitive sensing, we proposed a metal layer-assisted double-grating (MADG) structure with the evanescent field extending to the sensing region enabled by the metal reflector layer underneath the double-grating. The influence of structural parameters was systematically investigated. Bulk sensitivity of 550.0 nm/RIU and FOM of 1571.4 1/RIU were obtained after numerical optimization. Compared with a single-grating structure, the surface sensitivity of the double-grating structure for protein adsorption increases by a factor of 2.4 times. The as-proposed MADG has a great potential to be a biosensor with high sensitivity and high accuracy.https://www.mdpi.com/2079-6374/11/7/221sensorsguided-mode resonancefigure of meritgrating |
| spellingShingle | Chengrui Zhang Yi Zhou Lan Mi Jiong Ma Xiang Wu Yiyan Fei High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating Biosensors sensors guided-mode resonance figure of merit grating |
| title | High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating |
| title_full | High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating |
| title_fullStr | High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating |
| title_full_unstemmed | High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating |
| title_short | High Performance of a Metal Layer-Assisted Guided-Mode Resonance Biosensor Modulated by Double-Grating |
| title_sort | high performance of a metal layer assisted guided mode resonance biosensor modulated by double grating |
| topic | sensors guided-mode resonance figure of merit grating |
| url | https://www.mdpi.com/2079-6374/11/7/221 |
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