MicroRNA‐130a, a Potential Antifibrotic Target in Cardiac Fibrosis

MicroRNA‐130a, a Potential Antifibrotic Target in Cardiac Fibrosis

BackgroundCardiac fibrosis occurs because of disruption of the extracellular matrix network leading to myocardial dysfunction. Angiotensin II has been implicated in the development of cardiac fibrosis. Recently, microRNAs have been identified as an attractive target for therapeutic intervention in c...

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Bibliographic Details
Main Authors: Li Li, Kelsey R. Bounds, Piyali Chatterjee, Sudhiranjan Gupta
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiotensin II
cardiac fibrosis
miR‐130a
myofibroblast
peroxisome proliferator‐activated receptor γ
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.006763

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