Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system
Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new therapies are warranted. In this issue of the JCI, Goo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2022-10-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI164192 |
| _version_ | 1797634530009415680 |
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| author | Daniel J. Garry Demetris Yannopoulos Tamas Alexy |
| author_facet | Daniel J. Garry Demetris Yannopoulos Tamas Alexy |
| author_sort | Daniel J. Garry |
| collection | DOAJ |
| description | Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new therapies are warranted. In this issue of the JCI, Goodyer et al. used state-of-the-art technologies to image the cardiac conduction system (CCS) in real time and to deliver targeted therapies to the CCS and its subcomponents. These findings advance the ability to image and treat specific lineages within the adult heart with the potential for broader applications in the treatment of cardiovascular diseases. |
| first_indexed | 2024-03-11T12:10:05Z |
| format | Article |
| id | doaj.art-c24391fe2bfa433c9fec2046c3a5f3e0 |
| institution | Directory Open Access Journal |
| issn | 1558-8238 |
| language | English |
| last_indexed | 2024-03-11T12:10:05Z |
| publishDate | 2022-10-01 |
| publisher | American Society for Clinical Investigation |
| record_format | Article |
| series | The Journal of Clinical Investigation |
| spelling | doaj.art-c24391fe2bfa433c9fec2046c3a5f3e02023-11-07T16:19:26ZengAmerican Society for Clinical InvestigationThe Journal of Clinical Investigation1558-82382022-10-0113220Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction systemDaniel J. GarryDemetris YannopoulosTamas AlexyArrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new therapies are warranted. In this issue of the JCI, Goodyer et al. used state-of-the-art technologies to image the cardiac conduction system (CCS) in real time and to deliver targeted therapies to the CCS and its subcomponents. These findings advance the ability to image and treat specific lineages within the adult heart with the potential for broader applications in the treatment of cardiovascular diseases.https://doi.org/10.1172/JCI164192 |
| spellingShingle | Daniel J. Garry Demetris Yannopoulos Tamas Alexy Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system The Journal of Clinical Investigation |
| title | Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system |
| title_full | Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system |
| title_fullStr | Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system |
| title_full_unstemmed | Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system |
| title_short | Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system |
| title_sort | revolutionizing cardiovascular medicine targeted therapies for the cardiac conduction system |
| url | https://doi.org/10.1172/JCI164192 |
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