The Protective Effect of Garlic Extract on Diabetic Nephropathy

Dear Editor-in-Chief, Diabetes causes significant changes in urine and serum constituents such as albumin, creatinine, urea nitrogen, and glycated hemoglobin. Garlic extract, however, has been shown to restore all of these biochemicals, and cause histopathological changes. Administration of garlic...

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Main Authors: Mahmoud Rafieian-Kopaei, Shamin Ghobadi, Hamid Nasri
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2013-10-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/2884
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author Mahmoud Rafieian-Kopaei
Shamin Ghobadi
Hamid Nasri
author_facet Mahmoud Rafieian-Kopaei
Shamin Ghobadi
Hamid Nasri
author_sort Mahmoud Rafieian-Kopaei
collection DOAJ
description Dear Editor-in-Chief, Diabetes causes significant changes in urine and serum constituents such as albumin, creatinine, urea nitrogen, and glycated hemoglobin. Garlic extract, however, has been shown to restore all of these biochemicals, and cause histopathological changes. Administration of garlic extract or metformin, or their combinations has also been demonstrated to have both curative and protective effects against gentamicin nephrotoxicity. These findings can potentiate the clinical use of combinations of metformin and garlic extract in the prevention of diabetic nephropathy.
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spelling doaj.art-c24740f3ad084b8dbcdd05ce492c5cd62023-09-02T22:36:18ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2013-10-0131248126712691400The Protective Effect of Garlic Extract on Diabetic NephropathyMahmoud Rafieian-Kopaei0Shamin Ghobadi1Hamid Nasri2Professor, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, IranGeneral Practitioner, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, IranProfessor, Department of Nephrology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranDear Editor-in-Chief, Diabetes causes significant changes in urine and serum constituents such as albumin, creatinine, urea nitrogen, and glycated hemoglobin. Garlic extract, however, has been shown to restore all of these biochemicals, and cause histopathological changes. Administration of garlic extract or metformin, or their combinations has also been demonstrated to have both curative and protective effects against gentamicin nephrotoxicity. These findings can potentiate the clinical use of combinations of metformin and garlic extract in the prevention of diabetic nephropathy.http://jims.mui.ac.ir/index.php/jims/article/view/2884RenoprotectionGarlic extractNephropathyDiabetic nephropathy
spellingShingle Mahmoud Rafieian-Kopaei
Shamin Ghobadi
Hamid Nasri
The Protective Effect of Garlic Extract on Diabetic Nephropathy
مجله دانشکده پزشکی اصفهان
Renoprotection
Garlic extract
Nephropathy
Diabetic nephropathy
title The Protective Effect of Garlic Extract on Diabetic Nephropathy
title_full The Protective Effect of Garlic Extract on Diabetic Nephropathy
title_fullStr The Protective Effect of Garlic Extract on Diabetic Nephropathy
title_full_unstemmed The Protective Effect of Garlic Extract on Diabetic Nephropathy
title_short The Protective Effect of Garlic Extract on Diabetic Nephropathy
title_sort protective effect of garlic extract on diabetic nephropathy
topic Renoprotection
Garlic extract
Nephropathy
Diabetic nephropathy
url http://jims.mui.ac.ir/index.php/jims/article/view/2884
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